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Unveiling the G4-PAMAM capacity to bind and protect Ang-(1-7) bioactive peptide by molecular dynamics simulations

Angiotensin-(1-7) re-balance the Renin-Angiotensin system affected during several pathologies, including the new COVID-19; cardiovascular diseases; and cancer. However, one of the limiting factors for its therapeutic use is its short half-life, which might be overcome with the use of dendrimers as n...

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Detalles Bibliográficos
Autores principales: Chi, L. América, Asgharpour, Somayeh, Correa-Basurto, José, Bandala, Cindy Rodríguez, Martínez-Archundia, Marlet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358120/
https://www.ncbi.nlm.nih.gov/pubmed/35934747
http://dx.doi.org/10.1007/s10822-022-00470-5