Umbelliferone and scopoletin target tyrosine kinases on fibroblast-like synoviocytes to block NF-κB signaling to combat rheumatoid arthritis

Rheumatoid arthritis (RA) is a complex autoimmune condition primarily affecting synovial joints, which targeted synthetic drugs have damaging safety issues. Saussurea laniceps, a reputed anti-rheumatic medicinal herb, is an excellent place to start looking for natural products as safe, effective, ta...

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Detalles Bibliográficos
Autores principales: Chen, Qilei, Zhou, Wenmin, Huang, Yueming, Tian, Yuanyang, Wong, Sum Yi, Lam, Wing Ki, Ying, Ka Yee, Zhang, Jianye, Chen, Hubiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358226/
https://www.ncbi.nlm.nih.gov/pubmed/35959425
http://dx.doi.org/10.3389/fphar.2022.946210

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