Cargando…
Male factor testing in recurrent pregnancy loss cases: A narrative review
Recurrent pregnancy loss is a distinct disorder defined as the loss of at least 2 pregnancies before the 20 [Formula: see text] wk of gestation. With half of the genome of the embryo belonging to the father, the integrity of the sperm genome is crucial for a successful pregnancy. Semen analysis is r...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Knowledge E
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358234/ https://www.ncbi.nlm.nih.gov/pubmed/35958964 http://dx.doi.org/10.18502/ijrm.v20i6.11440 |
_version_ | 1784763884768329728 |
---|---|
author | Pourmasumi, Soheila Sabeti, Parvin Ghasemi, Nasrin |
author_facet | Pourmasumi, Soheila Sabeti, Parvin Ghasemi, Nasrin |
author_sort | Pourmasumi, Soheila |
collection | PubMed |
description | Recurrent pregnancy loss is a distinct disorder defined as the loss of at least 2 pregnancies before the 20 [Formula: see text] wk of gestation. With half of the genome of the embryo belonging to the father, the integrity of the sperm genome is crucial for a successful pregnancy. Semen analysis is recommended for men in such cases to evaluate sperm concentration, morphology, vitality and motility. However, other important sperm parameters such as sperm epigenetics, aneuploidy, Y chromosome microdeletion and chromatin integrity also correlate with successful pregnancy and delivery rate. This article examines the use of different sperm tests and their importance in male partners of women suffering from recurrent pregnancy loss. |
format | Online Article Text |
id | pubmed-9358234 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Knowledge E |
record_format | MEDLINE/PubMed |
spelling | pubmed-93582342022-08-10 Male factor testing in recurrent pregnancy loss cases: A narrative review Pourmasumi, Soheila Sabeti, Parvin Ghasemi, Nasrin Int J Reprod Biomed Review Article Recurrent pregnancy loss is a distinct disorder defined as the loss of at least 2 pregnancies before the 20 [Formula: see text] wk of gestation. With half of the genome of the embryo belonging to the father, the integrity of the sperm genome is crucial for a successful pregnancy. Semen analysis is recommended for men in such cases to evaluate sperm concentration, morphology, vitality and motility. However, other important sperm parameters such as sperm epigenetics, aneuploidy, Y chromosome microdeletion and chromatin integrity also correlate with successful pregnancy and delivery rate. This article examines the use of different sperm tests and their importance in male partners of women suffering from recurrent pregnancy loss. Knowledge E 2022-07-06 /pmc/articles/PMC9358234/ /pubmed/35958964 http://dx.doi.org/10.18502/ijrm.v20i6.11440 Text en Copyright © 2022 Pourmasumi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Pourmasumi, Soheila Sabeti, Parvin Ghasemi, Nasrin Male factor testing in recurrent pregnancy loss cases: A narrative review |
title | Male factor testing in recurrent pregnancy loss cases: A narrative review |
title_full | Male factor testing in recurrent pregnancy loss cases: A narrative review |
title_fullStr | Male factor testing in recurrent pregnancy loss cases: A narrative review |
title_full_unstemmed | Male factor testing in recurrent pregnancy loss cases: A narrative review |
title_short | Male factor testing in recurrent pregnancy loss cases: A narrative review |
title_sort | male factor testing in recurrent pregnancy loss cases: a narrative review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358234/ https://www.ncbi.nlm.nih.gov/pubmed/35958964 http://dx.doi.org/10.18502/ijrm.v20i6.11440 |
work_keys_str_mv | AT pourmasumisoheila malefactortestinginrecurrentpregnancylosscasesanarrativereview AT sabetiparvin malefactortestinginrecurrentpregnancylosscasesanarrativereview AT ghaseminasrin malefactortestinginrecurrentpregnancylosscasesanarrativereview |