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A WWP2–PTEN–KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice

WW domain–containing E3 Ubiquitin-protein ligase 2 (WWP2) has been found to positively regulate odontoblastic differentiation by monoubiquitinating the transcription factor Kruppel-like factor 5 (KLF5) in a cell culture system. However, the in vivo role of WWP2 in mouse teeth remains unknown. To exp...

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Detalles Bibliográficos
Autores principales:	Fu, Jing, Zhang, Xiaobo, Zheng, Huiwen, Yang, Guobin, Chen, Zhi, Yuan, Guohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358474/ https://www.ncbi.nlm.nih.gov/pubmed/35780838 http://dx.doi.org/10.1016/j.jbc.2022.102220

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