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Panax notoginseng saponin reduces IL-1β-stimulated apoptosis and endoplasmic reticulum stress of nucleus pulposus cells by suppressing miR-222-3p

BACKGROUND: It is well documented that the malignant biological behaviors of nucleus pulposus cells (NPCs) could trigger intervertebral disc degeneration (IDD). Panax notoginseng saponin (PNS) is a traditional Chinese medicine that inhibits osteoclastogenesis. However, its effects on the phenotypes...

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Detalles Bibliográficos
Autores principales: Zheng, Yuchen, Chen, Xiaosheng, Lan, Tao, Yan, Bin, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358501/
https://www.ncbi.nlm.nih.gov/pubmed/35957710
http://dx.doi.org/10.21037/atm-22-3203