Cargando…

GRSF1 predicts an unfavorable prognosis and promotes tumorigenesis in lung adenocarcinoma based on bioinformatics analysis and in vitro validation

BACKGROUND: Effective biomarkers play a critical role in improving clinical approaches to treat lung adenocarcinoma (LUAD). However, many existing biomarkers have limitations due to a lot of factors, requiring the development of additional biomarkers to effectively predict the disease course and pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Rong, Xu, Lin, Chen, Qichen, Tuersuntuoheti, Amannisa, Su, Luying, Xu, Fu, Bi, Yanqing, Deng, Yiqiao, Song, Wei, Zhao, Hong, Che, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358520/ https://www.ncbi.nlm.nih.gov/pubmed/35957724 http://dx.doi.org/10.21037/atm-22-2798

Ejemplares similares

GRSF1 suppresses cell senescence
por: Noh, Ji Heon, et al.
Publicado: (2018)

Upregulated long noncoding RNA PANDAR predicts an unfavorable prognosis and promotes tumorigenesis in cholangiocarcinoma
por: Xu, Yi, et al.
Publicado: (2017)

GRSF1 is an age-related regulator of senescence
por: Kim, Su-Jeong, et al.
Publicado: (2019)

CBX3 predicts an unfavorable prognosis and promotes tumorigenesis in osteosarcoma
por: Ma, Chao, et al.
Publicado: (2019)

GRSF1 Regulates RNA Processing in Mitochondrial RNA Granules
por: Jourdain, Alexis A., et al.
Publicado: (2013)

Overexpression of ZNF703 facilitates tumorigenesis and predicts unfavorable prognosis in patients with cholangiocarcinoma
por: Li, Keyu, et al.
Publicado: (2016)

GRSF1 deficiency in skeletal muscle reduces endurance in aged mice
por: Driscoll, Riley K., et al.
Publicado: (2021)

GRSF1 antagonizes age-associated hypercoagulability via modulation of fibrinogen mRNA stability
por: Liu, Doudou, et al.
Publicado: (2023)

Overexpression of WWP1 Promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma
por: Zhang, Xiao-Fei, et al.
Publicado: (2015)

An Externally Validated Dynamic Nomogram for Predicting Unfavorable Prognosis in Patients With Aneurysmal Subarachnoid Hemorrhage
por: Hu, Ping, et al.
Publicado: (2021)

Rab27b Is a Potential Indicator for Lymph Node Metastasis and Unfavorable Prognosis in Lung Adenocarcinoma
por: Zhang, Louqian, et al.
Publicado: (2018)

CASC2c as an unfavorable prognosis factor interacts with miR-101 to mediate astrocytoma tumorigenesis
por: Liu, Changhong, et al.
Publicado: (2017)

TINCR expression is associated with unfavorable prognosis in patients with hepatocellular carcinoma
por: Tian, Feng, et al.
Publicado: (2017)

Integrated analysis revealed hypoxia signatures and LDHA related to tumor cell dedifferentiation and unfavorable prognosis in pancreatic adenocarcinoma: Hypoxia in PDAC
por: Dong, Mingwei, et al.
Publicado: (2023)

Elevated glypican‐1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma
por: Lu, Haizhen, et al.
Publicado: (2017)

Overexpression of BCCIP predicts an unfavorable prognosis and promotes the proliferation and migration of lung adenocarcinoma
por: Shi, Jie, et al.
Publicado: (2021)

Grsf1-Induced Translation of the SNARE Protein Use1 Is Required for Expansion of the Erythroid Compartment
por: Nieradka, Andrzej, et al.
Publicado: (2014)

HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP
por: Noh, Ji Heon, et al.
Publicado: (2016)

Bioinformatics Identification of Key Genes for the Development and Prognosis of Lung Adenocarcinoma
por: Luo, Xuan, et al.
Publicado: (2022)

Unfavorable prognosis of nephroblastoma in adults
por: Huszno, Joanna, et al.
Publicado: (2013)

Risk factors and dynamic nomogram for unfavorable prognosis of Marchiafava–Bignami disease
por: Zhou, Zhiwei, et al.
Publicado: (2023)

High PD-1 expression level is associated with an unfavorable prognosis in patients with cervical adenocarcinoma
por: Ishikawa, Masako, et al.
Publicado: (2020)

Correlation of CD47 Expression with Adverse Clinicopathologic Features and an Unfavorable Prognosis in Colorectal Adenocarcinoma
por: Kim, Hyunsung, et al.
Publicado: (2021)

The PD-L1 Expression and Tumor-Infiltrating Immune Cells Predict an Unfavorable Prognosis in Pancreatic Ductal Adenocarcinoma and Adenosquamous Carcinoma
por: Zhang, Zhiwei, et al.
Publicado: (2023)

Comprehensive bioinformatics analyses of APOBECs family and identification of APOBEC3D as the unfavorable prognostic biomarker in clear cell renal cell carcinoma
por: Zhu, Zhenpeng, et al.
Publicado: (2021)

Geniposide Possesses the Protective Effect on Myocardial Injury by Inhibiting Oxidative Stress and Ferroptosis via Activation of the Grsf1/GPx4 Axis
por: Shen, Yuehong, et al.
Publicado: (2022)

Long non-coding RNA UCA1 indicates an unfavorable prognosis and promotes tumorigenesis via regulating AKT/GSK-3β signaling pathway in cholangiocarcinoma
por: Xu, Yi, et al.
Publicado: (2017)

Increased expression of TET3 predicts unfavorable prognosis in patients with ovarian cancer-a bioinformatics integrative analysis
por: Cao, Tiefeng, et al.
Publicado: (2019)

LncRNAs specifically overexpressed in endocervical adenocarcinoma are associated with an unfavorable recurrence prognosis and the immune response
por: Song, Yong, et al.
Publicado: (2021)

High Expression of COA6 Is Related to Unfavorable Prognosis and Enhanced Oxidative Phosphorylation in Lung Adenocarcinoma
por: Zhang, Ming, et al.
Publicado: (2023)

Loss of RNA-binding protein GRSF1 activates mTOR to elicit a proinflammatory transcriptional program
por: Noh, Ji Heon, et al.
Publicado: (2019)

Tumor-associated lymphangiogenesis predicts unfavorable prognosis of intrahepatic cholangiocarcinoma
por: Sha, Meng, et al.
Publicado: (2019)

KRT8 and KRT19, associated with EMT, are hypomethylated and overexpressed in lung adenocarcinoma and link to unfavorable prognosis
por: Wang, Wenlong, et al.
Publicado: (2020)

Copy-number-gain of telomerase reverse transcriptase (hTERT) is associated with an unfavorable prognosis in esophageal adenocarcinoma
por: Lyu, Su Ir, et al.
Publicado: (2023)

High expression levels of MAGE-A9 are correlated with unfavorable survival in lung adenocarcinoma
por: Zhai, Xiaolu, et al.
Publicado: (2015)

Upregulated ENC1 predicts unfavorable prognosis and correlates with immune infiltration in endometrial cancer
por: He, Lingling, et al.
Publicado: (2022)

Tescalcin is an unfavorable prognosis factor that regulats cell proliferation and survival in hepatocellular carcinoma patients
por: Zhou, Zhong‐Guo, et al.
Publicado: (2020)

Case Report: Successful Immunotherapy Improved the Prognosis of the Unfavorable Subset of Cancer of Unknown Primary
por: Mei, Jie, et al.
Publicado: (2022)

Identification of nine key genes by bioinformatics analysis for predicting poor prognosis in smoking-induced lung adenocarcinoma
por: Ren, Chuanli, et al.
Publicado: (2020)

Noncoding RNAs-mediated overexpression of KIF14 is associated with tumor immune infiltration and unfavorable prognosis in lung adenocarcinoma
por: Wang, Hong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m4837ievvsue799nu7hrbr7q7a