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Recognition and unfolding of human telomeric G-quadruplex by short peptide binding identified from the HRDC domain of BLM helicase

Research in recent decades has revealed that the guanine (G)-quadruplex secondary structure in DNA modulates a variety of cellular events that are mostly related to serious diseases. Systems capable of regulating DNA G-quadruplex structures would therefore be useful for the modulation of various cel...

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Detalles Bibliográficos
Autores principales: Sharma, Taniya, Kundu, Nikita, Kaur, Sarvpreet, Chakraborty, Amlan, Mahto, Aman Kumar, Dewangan, Rikeshwer Prasad, Shankaraswamy, Jadala, Saxena, Sarika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358547/
https://www.ncbi.nlm.nih.gov/pubmed/36043100
http://dx.doi.org/10.1039/d2ra03646k

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