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The association of maternal dietary quality and the antioxidant-proxidant balance of human milk
BACKGROUND: Human milk composition varies over time within an individual mother as well as between lactating mothers due to several factors including maternal health, diet, and nutritional status. Therefore, improving nutrition status during gestation and breastfeeding is crucial for improving the h...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358820/ https://www.ncbi.nlm.nih.gov/pubmed/35941627 http://dx.doi.org/10.1186/s13006-022-00498-1 |
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author | Karbasi, Samira Bahrami, Afsane Asadi, Zahra Shahbeiki, Fatemeh Naseri, Mohsen Zarban, Asghar Ferns, Gordon A. |
author_facet | Karbasi, Samira Bahrami, Afsane Asadi, Zahra Shahbeiki, Fatemeh Naseri, Mohsen Zarban, Asghar Ferns, Gordon A. |
author_sort | Karbasi, Samira |
collection | PubMed |
description | BACKGROUND: Human milk composition varies over time within an individual mother as well as between lactating mothers due to several factors including maternal health, diet, and nutritional status. Therefore, improving nutrition status during gestation and breastfeeding is crucial for improving the health of both mothers and infants. Diet can enhance the oxidant-antioxidant balance of human milk. This study aimed to investigate the association between human milk oxidant-antioxidant balance with dietary patterns of lactating mothers identified by using principal component analysis. METHOD: This cross-sectional study included 350 breastfeeding women between the ages of 20 to 35 years. The dietary intakes of the women in the study were estimated using a validated food frequency questionnaire, which included 65 food items. The oxidant-antioxidant balance of milk samples was assessed using the ferric reducing antioxidant power (FRAP), 2, 2′-diphenyl-1-picrylhydrazyl (DPPH), thiobarbituric acid reactive substances (TBARs), and Ellman’s assay. The milk concentration of total protein, calcium, and triglyceride was also measured using commercial kits. RESULT: Two predominant dietary patterns were recognized that we defined as a healthy and unhealthy pattern. There were higher levels of DPPH and thiol in the milk from mothers in the third tertile (highest adherence) of a healthy dietary pattern compared to the first tertile (lowest adherence; p < 0.05). Milk calcium and thiol were significantly lower in the third tertile of mothers with an unhealthy dietary pattern versus the first tertile (P < 0.05). In multivariate multinomial logistic regression analyses adjusted for mother’s age, body mass index (BMI), energy intake, and infant’s sex, adherence to a healthy dietary pattern was associated with higher levels of milk DPPH (OR = 1.32, 95% confidence interval (CI): 1.01, 1.80) and milk thiol (OR = 1.21, 95% CI: 1.10, 1.50). On the other adherence to the unhealthy dietary pattern was correlated with low levels of milk thiol (OR = 1.29; 95%CI: 1.09, 1.59) and milk calcium (OR = 1.28; 95%CI: 1.11, 1.55). CONCLUSION: Our findings demonstrated that adherence to a healthy dietary pattern, identified by higher consumption of green vegetables, other vegetables, and fruits is associated with a higher milk oxidant-antioxidant status in breastfeeding mothers. |
format | Online Article Text |
id | pubmed-9358820 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-93588202022-08-10 The association of maternal dietary quality and the antioxidant-proxidant balance of human milk Karbasi, Samira Bahrami, Afsane Asadi, Zahra Shahbeiki, Fatemeh Naseri, Mohsen Zarban, Asghar Ferns, Gordon A. Int Breastfeed J Research BACKGROUND: Human milk composition varies over time within an individual mother as well as between lactating mothers due to several factors including maternal health, diet, and nutritional status. Therefore, improving nutrition status during gestation and breastfeeding is crucial for improving the health of both mothers and infants. Diet can enhance the oxidant-antioxidant balance of human milk. This study aimed to investigate the association between human milk oxidant-antioxidant balance with dietary patterns of lactating mothers identified by using principal component analysis. METHOD: This cross-sectional study included 350 breastfeeding women between the ages of 20 to 35 years. The dietary intakes of the women in the study were estimated using a validated food frequency questionnaire, which included 65 food items. The oxidant-antioxidant balance of milk samples was assessed using the ferric reducing antioxidant power (FRAP), 2, 2′-diphenyl-1-picrylhydrazyl (DPPH), thiobarbituric acid reactive substances (TBARs), and Ellman’s assay. The milk concentration of total protein, calcium, and triglyceride was also measured using commercial kits. RESULT: Two predominant dietary patterns were recognized that we defined as a healthy and unhealthy pattern. There were higher levels of DPPH and thiol in the milk from mothers in the third tertile (highest adherence) of a healthy dietary pattern compared to the first tertile (lowest adherence; p < 0.05). Milk calcium and thiol were significantly lower in the third tertile of mothers with an unhealthy dietary pattern versus the first tertile (P < 0.05). In multivariate multinomial logistic regression analyses adjusted for mother’s age, body mass index (BMI), energy intake, and infant’s sex, adherence to a healthy dietary pattern was associated with higher levels of milk DPPH (OR = 1.32, 95% confidence interval (CI): 1.01, 1.80) and milk thiol (OR = 1.21, 95% CI: 1.10, 1.50). On the other adherence to the unhealthy dietary pattern was correlated with low levels of milk thiol (OR = 1.29; 95%CI: 1.09, 1.59) and milk calcium (OR = 1.28; 95%CI: 1.11, 1.55). CONCLUSION: Our findings demonstrated that adherence to a healthy dietary pattern, identified by higher consumption of green vegetables, other vegetables, and fruits is associated with a higher milk oxidant-antioxidant status in breastfeeding mothers. BioMed Central 2022-08-08 /pmc/articles/PMC9358820/ /pubmed/35941627 http://dx.doi.org/10.1186/s13006-022-00498-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Karbasi, Samira Bahrami, Afsane Asadi, Zahra Shahbeiki, Fatemeh Naseri, Mohsen Zarban, Asghar Ferns, Gordon A. The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
title | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
title_full | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
title_fullStr | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
title_full_unstemmed | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
title_short | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
title_sort | association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358820/ https://www.ncbi.nlm.nih.gov/pubmed/35941627 http://dx.doi.org/10.1186/s13006-022-00498-1 |
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