Identification and characterization of FGFR2(+) hematopoietic stem cell-derived fibrocytes as precursors of cancer-associated fibroblasts induced by esophageal squamous cell carcinoma

BACKGROUND: Cancer-associated fibroblast (CAF) is an ideal target for cancer treatment. Recent studies have focused on eliminating CAFs and their effects by targeting their markers or blocking individual CAF-secreted factors. However, these strategies have been limited by their specificity for targe...

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Detalles Bibliográficos
Autores principales: Qiu, Haibo, Zhang, Xu, Qi, Jiali, Zhang, Jiangwen, Tong, Yin, Li, Lei, Fu, Li, Qin, Yan-Ru, Guan, Xinyuan, Zhang, Liyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358838/
https://www.ncbi.nlm.nih.gov/pubmed/35941662
http://dx.doi.org/10.1186/s13046-022-02435-w

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