Apolipoprotein A5 ameliorates MCT induced pulmonary hypertension by inhibiting ER stress in a GRP78 dependent mechanism

BACKGROUND: Pulmonary arterial hypertension (PAH) is a chronic, progressive lung vascular disease accompanied by elevated pulmonary vascular pressure and resistance, and it is characterized by increased pulmonary artery smooth muscle cell (PASMC) proliferation. Apolipoprotein A5 (ApoA5) improves mon...

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Detalles Bibliográficos
Autores principales: Chen, Jingyuan, Luo, Jun, Qiu, Haihua, Tang, Yi, Yang, Xiaojie, Chen, Yusi, Li, Zilu, Li, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358849/
https://www.ncbi.nlm.nih.gov/pubmed/35941581
http://dx.doi.org/10.1186/s12944-022-01680-4

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