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MiR-520a-5p/PPP5C regulation pattern is identified as the key to gemcitabine resistance in pancreatic cancer

OBJECTIVE: To explore the effects of the expression level of miR-520-5p/PPP5C in pancreatic cancer cells and exosomes on cell viability, angiogenesis, autophagy, which involved in the mechanism of gemcitabine resistance in pancreatic cancer. METHODS: APSC-1 cell line was treated with gemcitabine, af...

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Detalles Bibliográficos
Autores principales: Fu, Ruibiao, Shao, Qian, Yang, Bin, Chen, Yan, Ye, Qinghuang, Chen, Xi, Zhu, Jinhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358958/
https://www.ncbi.nlm.nih.gov/pubmed/35957917
http://dx.doi.org/10.3389/fonc.2022.903484

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