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Mitochondrial impairment and repair in the pathogenesis of systemic lupus erythematosus

Nucleic acid autoantibodies, increase type I interferon (IFN-α) levels, and immune cell hyperactivation are hallmarks of systemic lupus erythematosus (SLE). Notably, immune cell activation requires high level of cellular energy that is predominately generated by the mitochondria. Mitochondrial react...

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Detalles Bibliográficos
Autores principales: Zhao, Like, Hu, Xianda, Xiao, Fei, Zhang, Xuan, Zhao, Lidan, Wang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9358979/
https://www.ncbi.nlm.nih.gov/pubmed/35958572
http://dx.doi.org/10.3389/fimmu.2022.929520