HTLV-1 intragenic viral enhancer influences immortalization phenotype in vitro, but is dispensable for persistence and disease development in animal models

Human T-cell leukemia virus type 1 (HTLV-1) is the causative infectious agent of adult T-cell leukemia/lymphoma (ATL) and chronic neurological disease. The disparity between silenced sense transcription versus constitutively active antisense (Hbz) transcription from the integrated provirus is not fu...

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Detalles Bibliográficos
Autores principales: Maksimova, Victoria, Smith, Susan, Seth, Jaideep, Phelps, Cameron, Niewiesk, Stefan, Satou, Yorifumi, Green, Patrick L., Panfil, Amanda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359075/
https://www.ncbi.nlm.nih.gov/pubmed/35958554
http://dx.doi.org/10.3389/fimmu.2022.954077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359075/
https://www.ncbi.nlm.nih.gov/pubmed/35958554
http://dx.doi.org/10.3389/fimmu.2022.954077

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