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Temporal Cortex Microarray Analysis Revealed Impaired Ribosomal Biogenesis and Hyperactivity of the Glutamatergic System: An Early Signature of Asymptomatic Alzheimer's Disease

Pathogenic aging is regarded as asymptomatic AD when there is no cognitive deficit except for neuropathology consistent with Alzheimer's disease. These individuals are highly susceptible to developing AD. Braak and Braak's theory specific to tau pathology illustrates that the brain's...

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Detalles Bibliográficos
Autores principales: Kumari, Ankita, Rahaman, Abdul, Zeng, Xin-An, Farooq, Muhammad Adil, Huang, Yanyan, Yao, Runyu, Ali, Murtaza, Ishrat, Romana, Ali, Rafat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359077/
https://www.ncbi.nlm.nih.gov/pubmed/35958988
http://dx.doi.org/10.3389/fnins.2022.966877