Case Report: Sustained complete remission on combination therapy with olaparib and pembrolizumab in BRCA2-mutated and PD-L1-positive metastatic cholangiocarcinoma after platinum derivate

Cholangiocarcinoma (CCA) still has a poor prognosis and remains a major therapeutic challenge. When curative resection is not possible, palliative systemic chemotherapy with gemcitabine and platinum derivate as first line followed by a 5-FU doublet combination as second line is the standard therapy....

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Detalles Bibliográficos
Autores principales: Zhou, Taotao, Mahn, Robert, Möhring, Christian, Sadeghlar, Farsaneh, Meyer, Carsten, Toma, Marieta, Kreppel, Barbara, Essler, Markus, Glowka, Tim, Matthaei, Hanno, Kalff, Jörg C., Strassburg, Christian P., Gonzalez-Carmona, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359099/
https://www.ncbi.nlm.nih.gov/pubmed/35957899
http://dx.doi.org/10.3389/fonc.2022.933943

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