Mfn2 is responsible for inhibition of the RIG-I/IRF7 pathway and activation of NLRP3 inflammasome in Seneca Valley virus-infected PK-15 cells to promote viral replication

Seneca Valley virus (SVV), a non-enveloped positive single-stranded virus can cause vesicular disease in swine. However, the mechanisms by which SVV activates an innate immune response remain unknown. Mitofusin-2 (MFN2), a mitochondria-shaping protein regulating mitochondrial fusion and fission, pla...

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Detalles Bibliográficos
Autores principales: Deng, HuiDan, Zhu, Song, Zhu, Ling, Sun, Jing, Ding, YuChun, Li, FengQin, Jian, ZhiJie, Zhao, Jun, Deng, LiShuang, Deng, JunLiang, Deng, YouTian, Guo, HongRui, Sun, XianGang, Lai, Si Yuan, Tang, HuaQiao, Cui, HengMin, Ge, Liang Peng, Xu, ZhiWen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359100/
https://www.ncbi.nlm.nih.gov/pubmed/35958608
http://dx.doi.org/10.3389/fimmu.2022.955671

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