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Intrinsic Folding Properties of the HLA-B27 Heavy Chain Revealed by Single Chain Trimer Versions of Peptide-Loaded Class I Major Histocompatibility Complex Molecules

Peptide-loaded Major Histocompatibility Complex (pMHC) class I molecules can be expressed in a single chain trimeric (SCT) format, composed of a specific peptide fused to the light chain beta-2 microglobulin (β2m) and MHC class I heavy chain (HC) by flexible linker peptides. pMHC SCTs have been used...

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Detalles Bibliográficos
Autores principales:	Lenart, Izabela, Truong, Linh-Huyen, Nguyen, Dinh Dung, Rasiukienė, Olga, Tsao, Edward, Armstrong, Jonathan, Kumar, Pankaj, McHugh, Kirsty, Pereira, Branca I., Maan, Balraj S., Garstka, Malgorzata A., Bowness, Paul, Blake, Neil, Powis, Simon J., Gould, Keith, Nesbeth, Darren, Antoniou, Antony N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359109/ https://www.ncbi.nlm.nih.gov/pubmed/35958592 http://dx.doi.org/10.3389/fimmu.2022.902135

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