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Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children

PURPOSE: The present study was performed to compare the optical quality of the eyes of myopic children before and after treatment with atropine eye drops of different concentrations. METHODS: In the study population of 71 patients (131 eyes), 34 patients (63 eyes) were given 0.01% atropine eye drops...

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Autores principales: Li, Weiran, Cao, Yiting, Zhou, Jibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359241/
https://www.ncbi.nlm.nih.gov/pubmed/35647992
http://dx.doi.org/10.4103/ijo.IJO_2886_21
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author Li, Weiran
Cao, Yiting
Zhou, Jibo
author_facet Li, Weiran
Cao, Yiting
Zhou, Jibo
author_sort Li, Weiran
collection PubMed
description PURPOSE: The present study was performed to compare the optical quality of the eyes of myopic children before and after treatment with atropine eye drops of different concentrations. METHODS: In the study population of 71 patients (131 eyes), 34 patients (63 eyes) were given 0.01% atropine eye drops and 37 patients (68 eyes) were given 0.05% atropine eye drops. The modulation transfer function (MTF) cutoff frequency, Strehl ratio, objective scattering index (OSI), and predicted visual acuities (PVAs 100%, 20%, and 9%) under different lighting conditions were measured before and after two weeks of atropine treatment. RESULTS: After using 0.05% atropine eye drops for two weeks, the Strehl ratio decreased from 0.27 ± 0.07 to 0.23 ± 0.07 (P = 0.0026), PVA 20% decreased from 1.15 ± 0.32 to 1.03 ± 0.36 (P = 0.0344), and PVA 9% decreased from 0.74 ± 0.23 to 0.64 ± 0.23 (P = 0.0073). The OSI was significantly higher after using 0.05% than 0.01% atropine eye drops (P = 0.0396), while both the Strehl ratio and PVA 20% were lower after using 0.05% than 0.01% atropine eye drops (P = 0.0087 and P = 0.0492, respectively). CONCLUSION: The children’s optical quality did not change significantly after using 0.01% atropine eye drops, whereas it decreased after using 0.05% atropine eye drops.
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spelling pubmed-93592412022-08-10 Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children Li, Weiran Cao, Yiting Zhou, Jibo Indian J Ophthalmol Special Focus, Pediatric Ophthalmology, Original Article PURPOSE: The present study was performed to compare the optical quality of the eyes of myopic children before and after treatment with atropine eye drops of different concentrations. METHODS: In the study population of 71 patients (131 eyes), 34 patients (63 eyes) were given 0.01% atropine eye drops and 37 patients (68 eyes) were given 0.05% atropine eye drops. The modulation transfer function (MTF) cutoff frequency, Strehl ratio, objective scattering index (OSI), and predicted visual acuities (PVAs 100%, 20%, and 9%) under different lighting conditions were measured before and after two weeks of atropine treatment. RESULTS: After using 0.05% atropine eye drops for two weeks, the Strehl ratio decreased from 0.27 ± 0.07 to 0.23 ± 0.07 (P = 0.0026), PVA 20% decreased from 1.15 ± 0.32 to 1.03 ± 0.36 (P = 0.0344), and PVA 9% decreased from 0.74 ± 0.23 to 0.64 ± 0.23 (P = 0.0073). The OSI was significantly higher after using 0.05% than 0.01% atropine eye drops (P = 0.0396), while both the Strehl ratio and PVA 20% were lower after using 0.05% than 0.01% atropine eye drops (P = 0.0087 and P = 0.0492, respectively). CONCLUSION: The children’s optical quality did not change significantly after using 0.01% atropine eye drops, whereas it decreased after using 0.05% atropine eye drops. Wolters Kluwer - Medknow 2022-06 2022-05-31 /pmc/articles/PMC9359241/ /pubmed/35647992 http://dx.doi.org/10.4103/ijo.IJO_2886_21 Text en Copyright: © 2022 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Special Focus, Pediatric Ophthalmology, Original Article
Li, Weiran
Cao, Yiting
Zhou, Jibo
Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children
title Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children
title_full Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children
title_fullStr Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children
title_full_unstemmed Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children
title_short Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children
title_sort effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children
topic Special Focus, Pediatric Ophthalmology, Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359241/
https://www.ncbi.nlm.nih.gov/pubmed/35647992
http://dx.doi.org/10.4103/ijo.IJO_2886_21
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