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Decoding glaucoma module premium edition
BACKGROUND: Traditional methods for neuroretinal rim width measurement in spectral domain optical coherence tomography (SD-OCT) employs the Bruch‘s membrane opening (BMO) as the anatomical border of the rim, referenced to a BMO horizontal reference plane, termed as “Bruch’s Membrane Opening-Horizont...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359262/ https://www.ncbi.nlm.nih.gov/pubmed/35648032 http://dx.doi.org/10.4103/ijo.IJO_1261_22 |
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author | Ramesh, Prasanna Venkatesh Parthasarathi, Sathyan Ramesh, Shruthy Vaishali Devadas, Aji Kunnath Ray, Prajnya Rajasekaran, Ramesh |
author_facet | Ramesh, Prasanna Venkatesh Parthasarathi, Sathyan Ramesh, Shruthy Vaishali Devadas, Aji Kunnath Ray, Prajnya Rajasekaran, Ramesh |
author_sort | Ramesh, Prasanna Venkatesh |
collection | PubMed |
description | BACKGROUND: Traditional methods for neuroretinal rim width measurement in spectral domain optical coherence tomography (SD-OCT) employs the Bruch‘s membrane opening (BMO) as the anatomical border of the rim, referenced to a BMO horizontal reference plane, termed as “Bruch’s Membrane Opening-Horizontal Rim Width” (BMO-HRW). BMO-HRW is defined as the distance between BMO and internal limiting membrane (ILM) on the horizontal plane. In contrast, the Spectralis OCT (Heidelberg Engineering, Germany) employs a new parameter called “Bruch’s Membrane Opening–Minimum Rim Width” (BMO-MRW) with Glaucoma Module Premium Edition (GMPE). GMPE provides a novel objective method of optic nerve head (ONH) analysis using BMO, but the neuroretinal rim assessment is performed from the BMO to the nearest point on the ILM, rather than on the horizontal reference plane. It is the BMO-MRW and is defined as the minimum distance between the BMO and ILM in the ONH. PURPOSE: In this video, anatomy of the ONH and GMPE is decoded from a neophyte user’s point of view, as to why BMO-MRW is more important than the traditional BMO-HRW for glaucoma evaluation. SYNOPSIS: The GMPE concepts are depicted in a novel dynamic (Clinical vs OCT Vs Histology) screenplay, detailing the below focal points with 2D & 3D animations: True Margin of ONH, Bruch’s Membrane (BM), Histology Vs OCT, BMO, Bruch’s Membrane Opening-Minimum Rim Width, Bruch’s Membrane Opening-Minimum Rim Width Versus Bruch’s Membrane Opening-Horizontal Rim Width, Alpha, Beta, Gamma Zone of ONH in OCT, Anatomic Positioning System, Impact of Fovea Bruch’s Membrane Opening Centre Axis. HIGHLIGHTS: This video also highlights, how with the advent of Anatomic Positioning System, scans were able to align relative to the individual’s Fovea-to-BMO-center (FoBMOC) axis at every follow-up, for accurately detecting changes, as small as 1 micron in BMO-MRW, thus creating a new world in diagnosing glaucoma and detecting glaucomatous progression with precision. VIDEO LINK: https://youtu.be/6RqF5guAziw |
format | Online Article Text |
id | pubmed-9359262 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-93592622022-08-10 Decoding glaucoma module premium edition Ramesh, Prasanna Venkatesh Parthasarathi, Sathyan Ramesh, Shruthy Vaishali Devadas, Aji Kunnath Ray, Prajnya Rajasekaran, Ramesh Indian J Ophthalmol IJO Videos BACKGROUND: Traditional methods for neuroretinal rim width measurement in spectral domain optical coherence tomography (SD-OCT) employs the Bruch‘s membrane opening (BMO) as the anatomical border of the rim, referenced to a BMO horizontal reference plane, termed as “Bruch’s Membrane Opening-Horizontal Rim Width” (BMO-HRW). BMO-HRW is defined as the distance between BMO and internal limiting membrane (ILM) on the horizontal plane. In contrast, the Spectralis OCT (Heidelberg Engineering, Germany) employs a new parameter called “Bruch’s Membrane Opening–Minimum Rim Width” (BMO-MRW) with Glaucoma Module Premium Edition (GMPE). GMPE provides a novel objective method of optic nerve head (ONH) analysis using BMO, but the neuroretinal rim assessment is performed from the BMO to the nearest point on the ILM, rather than on the horizontal reference plane. It is the BMO-MRW and is defined as the minimum distance between the BMO and ILM in the ONH. PURPOSE: In this video, anatomy of the ONH and GMPE is decoded from a neophyte user’s point of view, as to why BMO-MRW is more important than the traditional BMO-HRW for glaucoma evaluation. SYNOPSIS: The GMPE concepts are depicted in a novel dynamic (Clinical vs OCT Vs Histology) screenplay, detailing the below focal points with 2D & 3D animations: True Margin of ONH, Bruch’s Membrane (BM), Histology Vs OCT, BMO, Bruch’s Membrane Opening-Minimum Rim Width, Bruch’s Membrane Opening-Minimum Rim Width Versus Bruch’s Membrane Opening-Horizontal Rim Width, Alpha, Beta, Gamma Zone of ONH in OCT, Anatomic Positioning System, Impact of Fovea Bruch’s Membrane Opening Centre Axis. HIGHLIGHTS: This video also highlights, how with the advent of Anatomic Positioning System, scans were able to align relative to the individual’s Fovea-to-BMO-center (FoBMOC) axis at every follow-up, for accurately detecting changes, as small as 1 micron in BMO-MRW, thus creating a new world in diagnosing glaucoma and detecting glaucomatous progression with precision. VIDEO LINK: https://youtu.be/6RqF5guAziw Wolters Kluwer - Medknow 2022-06 /pmc/articles/PMC9359262/ /pubmed/35648032 http://dx.doi.org/10.4103/ijo.IJO_1261_22 Text en Copyright: © 2022 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | IJO Videos Ramesh, Prasanna Venkatesh Parthasarathi, Sathyan Ramesh, Shruthy Vaishali Devadas, Aji Kunnath Ray, Prajnya Rajasekaran, Ramesh Decoding glaucoma module premium edition |
title | Decoding glaucoma module premium edition |
title_full | Decoding glaucoma module premium edition |
title_fullStr | Decoding glaucoma module premium edition |
title_full_unstemmed | Decoding glaucoma module premium edition |
title_short | Decoding glaucoma module premium edition |
title_sort | decoding glaucoma module premium edition |
topic | IJO Videos |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359262/ https://www.ncbi.nlm.nih.gov/pubmed/35648032 http://dx.doi.org/10.4103/ijo.IJO_1261_22 |
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