Mesenchymal Stem Cell Derived Exosomes as Nanodrug Carrier of Doxorubicin for Targeted Osteosarcoma Therapy via SDF1-CXCR4 Axis

PURPOSE: The objective of this study was to investigate the antitumor activity, targeting capability, and mechanism of the developed nanodrug consisting of doxorubicin and exosome (Exo-Dox) derived from mesenchymal stem cells in vitro and in vivo. METHODS: The exosomes were isolated with Exosome Iso...

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Detalles Bibliográficos
Autores principales: Wei, Hongxiang, Chen, Fei, Chen, Jinyuan, Lin, Huangfeng, Wang, Shenglin, Wang, Yunqing, Wu, Chaoyang, Lin, Jianhua, Zhong, Guangxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359454/
https://www.ncbi.nlm.nih.gov/pubmed/35959282
http://dx.doi.org/10.2147/IJN.S372851

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