Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants

BACKGROUND: The continual emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern, in particular the newly emerged Omicron (B.1.1.529) variant and its BA.X lineages, has rendered ineffective a number of previously FDA emergency use authorized SARS-CoV-2 neutrali...

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Detalles Bibliográficos
Autores principales: Duty, J. Andrew, Kraus, Thomas, Zhou, Heyue, Zhang, Yanliang, Shaabani, Namir, Yildiz, Soner, Du, Na, Singh, Alok, Miorin, Lisa, Li, Donghui, Stegman, Karen, Ophir, Sabrina, Cao, Xia, Atanasoff, Kristina, Lim, Reyna, Mena, Ignacio, Bouvier, Nicole M., Kowdle, Shreyas, Carreño, Juan Manuel, Rivero-Nava, Laura, Raskin, Ariel, Moreno, Elena, Johnson, Sachi, Rathnasinghe, Raveen, Pai, Chin I., Kehrer, Thomas, Cabral, Elizabeth Paz, Jangra, Sonia, Healy, Laura, Singh, Gagandeep, Warang, Prajakta, Simon, Viviana, Sordillo, Emilia Mia, van Bakel, Harm, Liu, Yonghong, Sun, Weina, Kerwin, Lisa, Teijaro, John, Schotsaert, Michael, Krammer, Florian, Bresson, Damien, García-Sastre, Adolfo, Fu, Yanwen, Lee, Benhur, Powers, Colin, Moran, Thomas, Ji, Henry, Tortorella, Domenico, Allen, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Clinical and Translational Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359501/
https://www.ncbi.nlm.nih.gov/pubmed/36044897
http://dx.doi.org/10.1016/j.medj.2022.08.002

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