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Acute coronary syndrome versus acute myocarditis in young adults–value of speckle tracking echocardiography
PURPOSE: Comparing myocarditis with an acute coronary syndrome (ACS)-like presentation and acute myocardial infarction (AMI) poses an important clinical challenge. The purpose of the study was to investigate the diagnostic value of the clinical, laboratory and especially echocardiographic characteri...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359587/ https://www.ncbi.nlm.nih.gov/pubmed/35939417 http://dx.doi.org/10.1371/journal.pone.0271483 |
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author | Wieczorkiewicz, Paulina Supel, Karolina Przybylak, Katarzyna Kacprzak, Michal Zielinska, Marzenna |
author_facet | Wieczorkiewicz, Paulina Supel, Karolina Przybylak, Katarzyna Kacprzak, Michal Zielinska, Marzenna |
author_sort | Wieczorkiewicz, Paulina |
collection | PubMed |
description | PURPOSE: Comparing myocarditis with an acute coronary syndrome (ACS)-like presentation and acute myocardial infarction (AMI) poses an important clinical challenge. The purpose of the study was to investigate the diagnostic value of the clinical, laboratory and especially echocardiographic characteristics including speckle tracking echocardiography (STE) of patients with ACS-like myocarditis and AMI. METHODS: We conducted a retrospective analysis comparing 69 symptomatic patients (≤ 45 years old), hospitalized at the Department of Interventional Cardiology (Medical University of Lodz, Poland) between April 2014 and June 2021 with an initial diagnosis of ST-segment elevation myocardial infarction. RESULTS: 37 patients with the cardiac magnetic resonance–confirmed acute myocarditis and 32 patients diagnosed with AMI based on the clinical presentation, electrocardiogram and the presence of a culprit lesion on the coronary angiography were analysed including echocardiography parameters. On STE analysis an average global longitudinal (GLS), radial and circumferential strain including three—layers observation were significantly lower (absolute value) in patients with AMI versus acute myocarditis (p<0.05). There was no significant difference in Endo/Epi ratio (p = 0.144) between the groups. An average GLS < (-17.5) represented the optimal cut-off value for the myocarditis diagnosis. CONCLUSION: In patients with AMI a significant reduction of global and three-layers strains compared to patients with myocarditis was detected. Furthermore, our analysis also confirmed the discriminative pattern of myocardial injury between the groups. |
format | Online Article Text |
id | pubmed-9359587 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-93595872022-08-10 Acute coronary syndrome versus acute myocarditis in young adults–value of speckle tracking echocardiography Wieczorkiewicz, Paulina Supel, Karolina Przybylak, Katarzyna Kacprzak, Michal Zielinska, Marzenna PLoS One Research Article PURPOSE: Comparing myocarditis with an acute coronary syndrome (ACS)-like presentation and acute myocardial infarction (AMI) poses an important clinical challenge. The purpose of the study was to investigate the diagnostic value of the clinical, laboratory and especially echocardiographic characteristics including speckle tracking echocardiography (STE) of patients with ACS-like myocarditis and AMI. METHODS: We conducted a retrospective analysis comparing 69 symptomatic patients (≤ 45 years old), hospitalized at the Department of Interventional Cardiology (Medical University of Lodz, Poland) between April 2014 and June 2021 with an initial diagnosis of ST-segment elevation myocardial infarction. RESULTS: 37 patients with the cardiac magnetic resonance–confirmed acute myocarditis and 32 patients diagnosed with AMI based on the clinical presentation, electrocardiogram and the presence of a culprit lesion on the coronary angiography were analysed including echocardiography parameters. On STE analysis an average global longitudinal (GLS), radial and circumferential strain including three—layers observation were significantly lower (absolute value) in patients with AMI versus acute myocarditis (p<0.05). There was no significant difference in Endo/Epi ratio (p = 0.144) between the groups. An average GLS < (-17.5) represented the optimal cut-off value for the myocarditis diagnosis. CONCLUSION: In patients with AMI a significant reduction of global and three-layers strains compared to patients with myocarditis was detected. Furthermore, our analysis also confirmed the discriminative pattern of myocardial injury between the groups. Public Library of Science 2022-08-08 /pmc/articles/PMC9359587/ /pubmed/35939417 http://dx.doi.org/10.1371/journal.pone.0271483 Text en © 2022 Wieczorkiewicz et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Wieczorkiewicz, Paulina Supel, Karolina Przybylak, Katarzyna Kacprzak, Michal Zielinska, Marzenna Acute coronary syndrome versus acute myocarditis in young adults–value of speckle tracking echocardiography |
title | Acute coronary syndrome versus acute myocarditis in young adults–value of speckle tracking echocardiography |
title_full | Acute coronary syndrome versus acute myocarditis in young adults–value of speckle tracking echocardiography |
title_fullStr | Acute coronary syndrome versus acute myocarditis in young adults–value of speckle tracking echocardiography |
title_full_unstemmed | Acute coronary syndrome versus acute myocarditis in young adults–value of speckle tracking echocardiography |
title_short | Acute coronary syndrome versus acute myocarditis in young adults–value of speckle tracking echocardiography |
title_sort | acute coronary syndrome versus acute myocarditis in young adults–value of speckle tracking echocardiography |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359587/ https://www.ncbi.nlm.nih.gov/pubmed/35939417 http://dx.doi.org/10.1371/journal.pone.0271483 |
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