Cargando…

Epinephrine evokes shortening of human airway smooth muscle cells following β(2) adrenergic receptor desensitization

Epinephrine (EPI), an endogenous catecholamine involved in the body’s fight-or-flight responses to stress, activates α(1)-adrenergic receptors (α(1)ARs) expressed on various organs to evoke a wide range of physiological functions, including vasoconstriction. In the smooth muscle of human bronchi, ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deeney, Brian T., Cao, Gaoyuan, Orfanos, Sarah, Lee, Jordan, Kan, Mengyuan, Himes, Blanca E., Parikh, Vishal, Koziol-White, Cynthia J., An, Steven S., Panettieri, Reynold A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359643/ https://www.ncbi.nlm.nih.gov/pubmed/35787178 http://dx.doi.org/10.1152/ajplung.00444.2021

Ejemplares similares

Dexamethasone rescues TGF-β1-mediated β(2)-adrenergic receptor dysfunction and attenuates phosphodiesterase 4D expression in human airway smooth muscle cells
por: Chung, Elena, et al.
Publicado: (2020)

CEBPD modulates the airway smooth muscle transcriptomic response to glucocorticoids
por: Kan, Mengyuan, et al.
Publicado: (2022)

Airway Smooth Muscle–Specific Transcriptomic Signatures of Glucocorticoid Exposure
por: Kan, Mengyuan, et al.
Publicado: (2019)

Defective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe Asthma
por: Gupta, Manveen K., et al.
Publicado: (2015)

Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma
por: Himes, Blanca E., et al.
Publicado: (2015)

Inhibition of PI3K promotes dilation of human small airways in a rho kinase‐dependent manner
por: Koziol‐White, Cynthia J, et al.
Publicado: (2016)

FFAR1 activation attenuates histamine-induced myosin light chain phosphorylation and cortical tension development in human airway smooth muscle cells
por: Xu, Shengjie, et al.
Publicado: (2020)

STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma
por: Johnson, Martin T., et al.
Publicado: (2021)

The Bronchoprotective Effects of Dual Pharmacology, Muscarinic Receptor Antagonist and β(2) Adrenergic Receptor Agonist Navafenterol in Human Small Airways
por: Jude, Joseph Antony, et al.
Publicado: (2023)

TGF-β: The missing link in obesity-associated airway diseases?
por: Woo, Joanna, et al.
Publicado: (2021)

Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?
por: Amrani, Yassine, et al.
Publicado: (2000)

The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR
por: Huang, Jessie, et al.
Publicado: (2020)

Agonist-Directed Desensitization of the β(2)-Adrenergic Receptor
por: Goral, Vasiliy, et al.
Publicado: (2011)

MicroRNA Mediated Chemokine Responses in Human Airway Smooth Muscle Cells
por: Dileepan, Mythili, et al.
Publicado: (2016)

RNA-Seq Transcriptome Profiling Identifies CRISPLD2 as a Glucocorticoid Responsive Gene that Modulates Cytokine Function in Airway Smooth Muscle Cells
por: Himes, Blanca E., et al.
Publicado: (2014)

Rhinovirus induces airway remodeling: what are the physiological consequences?
por: Spector, Cassandra, et al.
Publicado: (2023)

MicroRNA-203 negatively regulates c-Abl, ERK1/2 phosphorylation, and proliferation in smooth muscle cells
por: Liao, Guoning, et al.
Publicado: (2015)

Using omics approaches to understand pulmonary diseases
por: Kan, Mengyuan, et al.
Publicado: (2017)

Benzo(a)pyrene triggers desensitization of β2-adrenergic pathway
por: Mayati, Abdullah, et al.
Publicado: (2017)

Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-α and dexamethasone
por: Tirumurugaan, Krishnaswamy G, et al.
Publicado: (2008)

Modulation of airway hyperresponsiveness by rhinovirus exposure
por: Lo, Dennis, et al.
Publicado: (2018)

Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling
por: Wang, Ruping, et al.
Publicado: (2022)

Effect of β(2)‐adrenergic receptor polymorphisms on epinephrine and exercise‐stimulated lipolysis in humans
por: Du, Shichun, et al.
Publicado: (2014)

β-Adrenergic Receptor Desensitization/Down-Regulation in Heart Failure: A Friend or Foe?
por: Mahmood, Abrahim, et al.
Publicado: (2022)

The presence of β(2)-adrenoceptors sensitizes α(2A)-adrenoceptors to desensitization after chronic epinephrine treatment
por: Bawa-Khalfe, Tasneem, et al.
Publicado: (2007)

Accumulating Evidence for Increased Velocity of Airway Smooth Muscle Shortening in Asthmatic Airway Hyperresponsiveness
por: Ijpma, Gijs, et al.
Publicado: (2012)

MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/AKT in human airway smooth muscle cells
por: Dileepan, Mythili, et al.
Publicado: (2014)

Epinephrine Use during Newborn Resuscitation
por: Kapadia, Vishal S., et al.
Publicado: (2017)

An RGS4-Mediated Phenotypic Switch of Bronchial Smooth Muscle Cells Promotes Fixed Airway Obstruction in Asthma
por: Damera, Gautam, et al.
Publicado: (2012)

α(1B)-Adrenergic Receptors Differentially Associate with Rab Proteins during Homologous and Heterologous Desensitization
por: Castillo-Badillo, Jean A., et al.
Publicado: (2015)

Corrigendum: Epinephrine Use During Newborn Resuscitation
por: Kapadia, Vishal S., et al.
Publicado: (2018)

Epinephrine penetrates through gingival sulcus unlike keratinized gingiva and evokes remote vasoconstriction in human
por: Vág, János, et al.
Publicado: (2020)

Defining an olfactory receptor function in airway smooth muscle cells
por: Aisenberg, William H., et al.
Publicado: (2016)

The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells
por: Syed, Farhat, et al.
Publicado: (2005)

An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling
por: Ghosh, Arnab, et al.
Publicado: (2020)

Functional NMDA receptors are expressed by human pulmonary artery smooth muscle cells
por: Dong, Yi Na, et al.
Publicado: (2021)

Canada’s First Joint Oncology-Allergy Clinic: Successful Desensitization to Trastuzumab Following Severe Anaphylactic Reaction in Which Epinephrine Was Inappropriately Withheld
por: Robinson, Madeline, et al.
Publicado: (2023)

394 Desensitization Protocol to Methotrexate
por: Maya, Jonathan, et al.
Publicado: (2012)

Characterising the Mechanism of Airway Smooth Muscle β(2) Adrenoceptor Desensitization by Rhinovirus Infected Bronchial Epithelial Cells
por: Van Ly, David, et al.
Publicado: (2013)

Anaphylatoxin C3a receptors in asthma
por: Ali, Hydar, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_9ijpk6gk9n3kehvee9r48r00bn