Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases

Due to the increasing population of individualswith cardiovascular diseases and related comorbidities, there is an increasing need for development of synergistic therapeutics. Monocytes are implicated in a broad spectrum of diseases and can serve as a focal point for therapeutic targeting. This revi...

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Detalles Bibliográficos
Autores principales: Aldarondo, Dasia, Wayne, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359644/
https://www.ncbi.nlm.nih.gov/pubmed/35085623
http://dx.doi.org/10.1016/j.addr.2022.114116
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author Aldarondo, Dasia
Wayne, Elizabeth
author_facet Aldarondo, Dasia
Wayne, Elizabeth
author_sort Aldarondo, Dasia
collection PubMed
description Due to the increasing population of individualswith cardiovascular diseases and related comorbidities, there is an increasing need for development of synergistic therapeutics. Monocytes are implicated in a broad spectrum of diseases and can serve as a focal point for therapeutic targeting. This review discusses the role of monocytes in cardiovascular diseases and highlights trends in monocyte targets nanoparticles in three cardiovascular-related diseases: Diabetes, Atherosclerosis, and HIV. Finally, the review offers perspectives on how to develop nanoparticle monocyte targeting strategies that can be beneficial for treating co-morbidities.
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spelling pubmed-93596442022-08-09 Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases Aldarondo, Dasia Wayne, Elizabeth Adv Drug Deliv Rev Article Due to the increasing population of individualswith cardiovascular diseases and related comorbidities, there is an increasing need for development of synergistic therapeutics. Monocytes are implicated in a broad spectrum of diseases and can serve as a focal point for therapeutic targeting. This review discusses the role of monocytes in cardiovascular diseases and highlights trends in monocyte targets nanoparticles in three cardiovascular-related diseases: Diabetes, Atherosclerosis, and HIV. Finally, the review offers perspectives on how to develop nanoparticle monocyte targeting strategies that can be beneficial for treating co-morbidities. 2022-03 2022-01-24 /pmc/articles/PMC9359644/ /pubmed/35085623 http://dx.doi.org/10.1016/j.addr.2022.114116 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Article
Aldarondo, Dasia
Wayne, Elizabeth
Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases
title Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases
title_full Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases
title_fullStr Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases
title_full_unstemmed Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases
title_short Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases
title_sort monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359644/
https://www.ncbi.nlm.nih.gov/pubmed/35085623
http://dx.doi.org/10.1016/j.addr.2022.114116
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