PGC1α/β Expression Predicts Therapeutic Response to Oxidative Phosphorylation Inhibition in Ovarian Cancer

Ovarian cancer is the deadliest gynecologic cancer, and novel therapeutic options are crucial to improve overall survival. Here we provide evidence that impairment of oxidative phosphorylation (OXPHOS) can help control ovarian cancer progression, and this benefit correlates with expression of the tw...

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Detalles Bibliográficos
Autores principales: Ghilardi, Carmen, Moreira-Barbosa, Catarina, Brunelli, Laura, Ostano, Paola, Panini, Nicolò, Lupi, Monica, Anastasia, Alessia, Fiordaliso, Fabio, Salio, Monica, Formenti, Laura, Russo, Massimo, Arrigoni, Edoardo, Chiaradonna, Ferdinando, Chiorino, Giovanna, Draetta, Giulio, Marszalek, Joseph R., Vellano, Christopher P., Pastorelli, Roberta, Bani, MariaRosa, Decio, Alessandra, Giavazzi, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359716/
https://www.ncbi.nlm.nih.gov/pubmed/35131872
http://dx.doi.org/10.1158/0008-5472.CAN-21-1223

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