Targeting Podoplanin for the Treatment of Osteosarcoma

PURPOSE: Osteosarcoma, the most common bone malignancy in children, has a poor prognosis, especially when the tumor metastasizes to the lungs. Therefore, novel therapeutic strategies targeting both proliferation and metastasis of osteosarcoma are required. Podoplanin (PDPN) is expressed by various t...

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Detalles Bibliográficos
Autores principales: Takemoto, Ai, Takagi, Satoshi, Ukaji, Takao, Gyobu, Nobuhiko, Kakino, Mamoru, Takami, Miho, Kobayashi, Asami, Lebel, Marie, Kawaguchi, Tokuichi, Sugawara, Minoru, Tsuji-Takayama, Kazue, Ichihara, Kenji, Funauchi, Yuki, Ae, Keisuke, Matsumoto, Seiichi, Sugiura, Yoshiya, Takeuchi, Kengo, Noda, Tetsuo, Katayama, Ryohei, Fujita, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359727/
https://www.ncbi.nlm.nih.gov/pubmed/35381070
http://dx.doi.org/10.1158/1078-0432.CCR-21-4509

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