RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1

RNA helicases are dysregulated in tumors. Here, we identified DHX37 as one of the top RNA helicase genes with upregulated expression in hepatocellular carcinoma (HCC). DHX37 promoted proliferation of liver cancer cells in vitro and in vivo. Epigenomic profiling of DHX37-knockdown and control HCC cel...

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Detalles Bibliográficos
Autores principales: Liu, Zhen, Ye, Youqiong, Liu, Yizhe, Liu, Yanfang, Chen, Huifang, Shen, Mengting, Wang, Zhen, Huang, Shenglin, Han, Leng, Chen, Zhiao, He, Xianghuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Molecular Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359749/
https://www.ncbi.nlm.nih.gov/pubmed/35290436
http://dx.doi.org/10.1158/0008-5472.CAN-21-3038

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