Imbalance between alpha-1-antitrypsin and interleukin 6 is associated with in-hospital mortality and thrombosis during COVID-19

Thrombosis is a hallmark of severe COVID-19. Alpha-1-antitrypsin (AAT), an inflammation-inducible serpin with anti-inflammatory, tissue protective and anticoagulant properties may be involved in severe COVID-19 pathophysiology including thrombosis onset. In this study, we examined AAT ability to pre...

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Detalles Bibliográficos
Autores principales: Philippe, Aurélien, Puel, Mathilde, Narjoz, Céline, Gendron, Nicolas, Durey-Dragon, Marie Agnès, Vedie, Benoit, Balduyck, Malika, Chocron, Richard, Hauw-Berlemont, Caroline, Sanchez, Olivier, Mirault, Tristan, Diehl, Jean-Luc, Smadja, David M., Loriot, Marie Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359756/
https://www.ncbi.nlm.nih.gov/pubmed/35952950
http://dx.doi.org/10.1016/j.biochi.2022.07.012

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