SILAC-based chemoproteomics reveals a neoligan analogue as an anti-inflammatory agent targeting IRGM to ameliorate cytokine storm

Cytokine storm is a key feature of sepsis and severe stage of COVID-19, and the immunosuppression after excessive immune activation is a substantial hazard to human life. Both pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) are recognized by various pa...

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Detalles Bibliográficos
Autores principales: Zhang, Jichao, Li, Yang, Meng, Guibing, Lu, Kui, Yan, Jiankun, Wu, Jiangpeng, Li, Pengyan, Luo, Lingling, Chen, Xi, Zhao, Xia, Qiu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359778/
https://www.ncbi.nlm.nih.gov/pubmed/35970074
http://dx.doi.org/10.1016/j.ejmech.2022.114659

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