Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues

OBJECTIVE: We aim to quantify the absolute protein expression of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) in various cells and tissues to determine the relative contribution of COX-1 and COX-2 to PGE(2) production. METHODS: An LC-MS method was developed and validated, then used for quan...

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Detalles Bibliográficos
Autores principales: Li, Li, Sun, Rongjin, Zenga, Joseph, Himburg, Heather, Wang, Lu, Duan, Shengnan, Liu, Jingwen, Bui, Dinh, Xie, Zuoxu, Du, Ting, Xie, Lijun, Yin, Taijun, Wong, Stu, Gao, Song, Hu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359786/
https://www.ncbi.nlm.nih.gov/pubmed/35958187
http://dx.doi.org/10.2147/JIR.S365842

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