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Clinical Effect of Renal Arterial Sympathetic Radiofrequency Ablation on Secondary Hypertension
Sympathetic hyperactivity is one of the main mechanisms of secondary hypertension. Reducing renal sympathetic activity through surgery can effectively reduce blood pressure. Many cases have shown that renal denervation (RDN) can selectively block renal artery sympathetic nerve activity to control re...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359839/ https://www.ncbi.nlm.nih.gov/pubmed/35959345 http://dx.doi.org/10.1155/2022/9948057 |
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author | Zhang, Hui Huang, Ting Shen, Jie Zou, Yuanlin Deng, Yunchao Hou, Min Huang, Xiang |
author_facet | Zhang, Hui Huang, Ting Shen, Jie Zou, Yuanlin Deng, Yunchao Hou, Min Huang, Xiang |
author_sort | Zhang, Hui |
collection | PubMed |
description | Sympathetic hyperactivity is one of the main mechanisms of secondary hypertension. Reducing renal sympathetic activity through surgery can effectively reduce blood pressure. Many cases have shown that renal denervation (RDN) can selectively block renal artery sympathetic nerve activity to control refractory hypertension. This surgery is a minimally invasive surgery, and the risk of surgery-related adverse events is significantly reduced compared with surgery. Therefore, the purpose of this study is to explore the efficacy of radiofrequency ablation of renal artery sympathetic nerve in the treatment of secondary hypertension. Eight patients with secondary hypertension diagnosed by the cardiovascular department of our hospital and treated with RDN were followed up for 3-18 months, of which 5 cases were followed up for more than 12 months and 8 cases were followed up for more than 3 months. Eight patients were treated with radiofrequency ablation of renal artery catheter. The parameters such as preoperative blood pressure, antihypertensive drugs, organ function, intraoperative ablation resistance, power, time, and temperature were determined. The related changes of blood pressure, antihypertensive drugs, and visceral function and the occurrence of side effects at 1 week and 1, 3, 6, and 12 months after operation were related to the operation. In conclusion, RDN has a significant clinical effect in the treatment of refractory hypertension, with stable postoperative blood pressure drop, reduced drug dosage, and less side effects. |
format | Online Article Text |
id | pubmed-9359839 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-93598392022-08-10 Clinical Effect of Renal Arterial Sympathetic Radiofrequency Ablation on Secondary Hypertension Zhang, Hui Huang, Ting Shen, Jie Zou, Yuanlin Deng, Yunchao Hou, Min Huang, Xiang Comput Math Methods Med Research Article Sympathetic hyperactivity is one of the main mechanisms of secondary hypertension. Reducing renal sympathetic activity through surgery can effectively reduce blood pressure. Many cases have shown that renal denervation (RDN) can selectively block renal artery sympathetic nerve activity to control refractory hypertension. This surgery is a minimally invasive surgery, and the risk of surgery-related adverse events is significantly reduced compared with surgery. Therefore, the purpose of this study is to explore the efficacy of radiofrequency ablation of renal artery sympathetic nerve in the treatment of secondary hypertension. Eight patients with secondary hypertension diagnosed by the cardiovascular department of our hospital and treated with RDN were followed up for 3-18 months, of which 5 cases were followed up for more than 12 months and 8 cases were followed up for more than 3 months. Eight patients were treated with radiofrequency ablation of renal artery catheter. The parameters such as preoperative blood pressure, antihypertensive drugs, organ function, intraoperative ablation resistance, power, time, and temperature were determined. The related changes of blood pressure, antihypertensive drugs, and visceral function and the occurrence of side effects at 1 week and 1, 3, 6, and 12 months after operation were related to the operation. In conclusion, RDN has a significant clinical effect in the treatment of refractory hypertension, with stable postoperative blood pressure drop, reduced drug dosage, and less side effects. Hindawi 2022-08-01 /pmc/articles/PMC9359839/ /pubmed/35959345 http://dx.doi.org/10.1155/2022/9948057 Text en Copyright © 2022 Hui Zhang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Zhang, Hui Huang, Ting Shen, Jie Zou, Yuanlin Deng, Yunchao Hou, Min Huang, Xiang Clinical Effect of Renal Arterial Sympathetic Radiofrequency Ablation on Secondary Hypertension |
title | Clinical Effect of Renal Arterial Sympathetic Radiofrequency Ablation on Secondary Hypertension |
title_full | Clinical Effect of Renal Arterial Sympathetic Radiofrequency Ablation on Secondary Hypertension |
title_fullStr | Clinical Effect of Renal Arterial Sympathetic Radiofrequency Ablation on Secondary Hypertension |
title_full_unstemmed | Clinical Effect of Renal Arterial Sympathetic Radiofrequency Ablation on Secondary Hypertension |
title_short | Clinical Effect of Renal Arterial Sympathetic Radiofrequency Ablation on Secondary Hypertension |
title_sort | clinical effect of renal arterial sympathetic radiofrequency ablation on secondary hypertension |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359839/ https://www.ncbi.nlm.nih.gov/pubmed/35959345 http://dx.doi.org/10.1155/2022/9948057 |
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