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A novel multimeric sCD19‐streptavidin fusion protein for functional detection and selective expansion of CD19‐targeted CAR‐T cells

BACKGROUND: CARs are engineered receptors comprising an immunoglobulin single‐chain variable fragment (scFv) that identifies and binds to the target antigen, a transmembrane domain, and an intracellular T‐cell signaling domain. CD19 is a B lineage‐specific transmembrane glycoprotein and is expressed...

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Detalles Bibliográficos
Autores principales:	Lian, Hui, Jiang, Jinhong, Wang, Yao, Yu, Xiaoxiao, Zheng, Rong, Long, Jing, Zhou, Mengjie, Zhou, Shirong, Wei, Cheng, Zhao, Ai, Gao, Jimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359867/ https://www.ncbi.nlm.nih.gov/pubmed/35621033 http://dx.doi.org/10.1002/cam4.4657

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