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Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy

PURPOSE: Most studies have investigated the differences in postgastrectomy quality of life (QOL) based on the surgical procedure or reconstruction method adopted; only a few studies have compared QOL based on tumor location. This large-scale study aims to investigate the differences in QOL between p...

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Autores principales: Fujisaki, Muneharu, Nomura, Takashi, Yamashita, Hiroharu, Uenosono, Yoshikazu, Fukunaga, Tetsu, Otsuji, Eigo, Takahashi, Masahiro, Matsumoto, Hideo, Oshio, Atsushi, Nakada, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Gastric Cancer Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359888/
https://www.ncbi.nlm.nih.gov/pubmed/35938369
http://dx.doi.org/10.5230/jgc.2022.22.e23
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author Fujisaki, Muneharu
Nomura, Takashi
Yamashita, Hiroharu
Uenosono, Yoshikazu
Fukunaga, Tetsu
Otsuji, Eigo
Takahashi, Masahiro
Matsumoto, Hideo
Oshio, Atsushi
Nakada, Koji
author_facet Fujisaki, Muneharu
Nomura, Takashi
Yamashita, Hiroharu
Uenosono, Yoshikazu
Fukunaga, Tetsu
Otsuji, Eigo
Takahashi, Masahiro
Matsumoto, Hideo
Oshio, Atsushi
Nakada, Koji
author_sort Fujisaki, Muneharu
collection PubMed
description PURPOSE: Most studies have investigated the differences in postgastrectomy quality of life (QOL) based on the surgical procedure or reconstruction method adopted; only a few studies have compared QOL based on tumor location. This large-scale study aims to investigate the differences in QOL between patients with esophagogastric junction cancer (EGJC) and those with upper third gastric cancer (UGC) undergoing the same gastrectomy procedure to evaluate the impact of tumor location on postoperative QOL. METHODS: The Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire was distributed in 70 institutions to 2,364 patients who underwent gastrectomy for EGJC or UGC. A total of 1,909 patients were eligible for the study, and 1,744 patients who underwent total gastrectomy (TG) or proximal gastrectomy (PG) were selected for the final analysis. These patients were divided into EGJC and UGC groups; thereafter, the PGSAS-45 main outcome measures (MOMs) were compared between the two groups for each type of gastrectomy. RESULTS: Among the post-TG patients, only one MOM was significantly better in the UGC group than in the EGJC group. Conversely, among the post-PG patients, postoperative QOL was significantly better in 6 out of 19 MOMs in the UGC group than in the EGJC group. CONCLUSIONS: Tumor location had a minimal effect on the postoperative QOL of post-TG patients, whereas among post-PG patients, there were definite differences in postoperative QOL between the two groups. It seems reasonable to conservatively estimate the benefits of PG in patients with EGJC compared to those in patients with UGC.
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spelling pubmed-93598882022-08-19 Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy Fujisaki, Muneharu Nomura, Takashi Yamashita, Hiroharu Uenosono, Yoshikazu Fukunaga, Tetsu Otsuji, Eigo Takahashi, Masahiro Matsumoto, Hideo Oshio, Atsushi Nakada, Koji J Gastric Cancer Original Article PURPOSE: Most studies have investigated the differences in postgastrectomy quality of life (QOL) based on the surgical procedure or reconstruction method adopted; only a few studies have compared QOL based on tumor location. This large-scale study aims to investigate the differences in QOL between patients with esophagogastric junction cancer (EGJC) and those with upper third gastric cancer (UGC) undergoing the same gastrectomy procedure to evaluate the impact of tumor location on postoperative QOL. METHODS: The Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire was distributed in 70 institutions to 2,364 patients who underwent gastrectomy for EGJC or UGC. A total of 1,909 patients were eligible for the study, and 1,744 patients who underwent total gastrectomy (TG) or proximal gastrectomy (PG) were selected for the final analysis. These patients were divided into EGJC and UGC groups; thereafter, the PGSAS-45 main outcome measures (MOMs) were compared between the two groups for each type of gastrectomy. RESULTS: Among the post-TG patients, only one MOM was significantly better in the UGC group than in the EGJC group. Conversely, among the post-PG patients, postoperative QOL was significantly better in 6 out of 19 MOMs in the UGC group than in the EGJC group. CONCLUSIONS: Tumor location had a minimal effect on the postoperative QOL of post-TG patients, whereas among post-PG patients, there were definite differences in postoperative QOL between the two groups. It seems reasonable to conservatively estimate the benefits of PG in patients with EGJC compared to those in patients with UGC. The Korean Gastric Cancer Association 2022-07 2022-07-31 /pmc/articles/PMC9359888/ /pubmed/35938369 http://dx.doi.org/10.5230/jgc.2022.22.e23 Text en Copyright © 2022. Korean Gastric Cancer Association https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Fujisaki, Muneharu
Nomura, Takashi
Yamashita, Hiroharu
Uenosono, Yoshikazu
Fukunaga, Tetsu
Otsuji, Eigo
Takahashi, Masahiro
Matsumoto, Hideo
Oshio, Atsushi
Nakada, Koji
Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy
title Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy
title_full Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy
title_fullStr Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy
title_full_unstemmed Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy
title_short Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy
title_sort impact of tumor location on the quality of life of patients undergoing total or proximal gastrectomy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359888/
https://www.ncbi.nlm.nih.gov/pubmed/35938369
http://dx.doi.org/10.5230/jgc.2022.22.e23
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