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Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy
PURPOSE: Most studies have investigated the differences in postgastrectomy quality of life (QOL) based on the surgical procedure or reconstruction method adopted; only a few studies have compared QOL based on tumor location. This large-scale study aims to investigate the differences in QOL between p...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Gastric Cancer Association
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359888/ https://www.ncbi.nlm.nih.gov/pubmed/35938369 http://dx.doi.org/10.5230/jgc.2022.22.e23 |
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author | Fujisaki, Muneharu Nomura, Takashi Yamashita, Hiroharu Uenosono, Yoshikazu Fukunaga, Tetsu Otsuji, Eigo Takahashi, Masahiro Matsumoto, Hideo Oshio, Atsushi Nakada, Koji |
author_facet | Fujisaki, Muneharu Nomura, Takashi Yamashita, Hiroharu Uenosono, Yoshikazu Fukunaga, Tetsu Otsuji, Eigo Takahashi, Masahiro Matsumoto, Hideo Oshio, Atsushi Nakada, Koji |
author_sort | Fujisaki, Muneharu |
collection | PubMed |
description | PURPOSE: Most studies have investigated the differences in postgastrectomy quality of life (QOL) based on the surgical procedure or reconstruction method adopted; only a few studies have compared QOL based on tumor location. This large-scale study aims to investigate the differences in QOL between patients with esophagogastric junction cancer (EGJC) and those with upper third gastric cancer (UGC) undergoing the same gastrectomy procedure to evaluate the impact of tumor location on postoperative QOL. METHODS: The Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire was distributed in 70 institutions to 2,364 patients who underwent gastrectomy for EGJC or UGC. A total of 1,909 patients were eligible for the study, and 1,744 patients who underwent total gastrectomy (TG) or proximal gastrectomy (PG) were selected for the final analysis. These patients were divided into EGJC and UGC groups; thereafter, the PGSAS-45 main outcome measures (MOMs) were compared between the two groups for each type of gastrectomy. RESULTS: Among the post-TG patients, only one MOM was significantly better in the UGC group than in the EGJC group. Conversely, among the post-PG patients, postoperative QOL was significantly better in 6 out of 19 MOMs in the UGC group than in the EGJC group. CONCLUSIONS: Tumor location had a minimal effect on the postoperative QOL of post-TG patients, whereas among post-PG patients, there were definite differences in postoperative QOL between the two groups. It seems reasonable to conservatively estimate the benefits of PG in patients with EGJC compared to those in patients with UGC. |
format | Online Article Text |
id | pubmed-9359888 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Korean Gastric Cancer Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-93598882022-08-19 Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy Fujisaki, Muneharu Nomura, Takashi Yamashita, Hiroharu Uenosono, Yoshikazu Fukunaga, Tetsu Otsuji, Eigo Takahashi, Masahiro Matsumoto, Hideo Oshio, Atsushi Nakada, Koji J Gastric Cancer Original Article PURPOSE: Most studies have investigated the differences in postgastrectomy quality of life (QOL) based on the surgical procedure or reconstruction method adopted; only a few studies have compared QOL based on tumor location. This large-scale study aims to investigate the differences in QOL between patients with esophagogastric junction cancer (EGJC) and those with upper third gastric cancer (UGC) undergoing the same gastrectomy procedure to evaluate the impact of tumor location on postoperative QOL. METHODS: The Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire was distributed in 70 institutions to 2,364 patients who underwent gastrectomy for EGJC or UGC. A total of 1,909 patients were eligible for the study, and 1,744 patients who underwent total gastrectomy (TG) or proximal gastrectomy (PG) were selected for the final analysis. These patients were divided into EGJC and UGC groups; thereafter, the PGSAS-45 main outcome measures (MOMs) were compared between the two groups for each type of gastrectomy. RESULTS: Among the post-TG patients, only one MOM was significantly better in the UGC group than in the EGJC group. Conversely, among the post-PG patients, postoperative QOL was significantly better in 6 out of 19 MOMs in the UGC group than in the EGJC group. CONCLUSIONS: Tumor location had a minimal effect on the postoperative QOL of post-TG patients, whereas among post-PG patients, there were definite differences in postoperative QOL between the two groups. It seems reasonable to conservatively estimate the benefits of PG in patients with EGJC compared to those in patients with UGC. The Korean Gastric Cancer Association 2022-07 2022-07-31 /pmc/articles/PMC9359888/ /pubmed/35938369 http://dx.doi.org/10.5230/jgc.2022.22.e23 Text en Copyright © 2022. Korean Gastric Cancer Association https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Fujisaki, Muneharu Nomura, Takashi Yamashita, Hiroharu Uenosono, Yoshikazu Fukunaga, Tetsu Otsuji, Eigo Takahashi, Masahiro Matsumoto, Hideo Oshio, Atsushi Nakada, Koji Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy |
title | Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy |
title_full | Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy |
title_fullStr | Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy |
title_full_unstemmed | Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy |
title_short | Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy |
title_sort | impact of tumor location on the quality of life of patients undergoing total or proximal gastrectomy |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359888/ https://www.ncbi.nlm.nih.gov/pubmed/35938369 http://dx.doi.org/10.5230/jgc.2022.22.e23 |
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