Prospective evaluation of immunological, molecular-genetic, image-based and microbial analyses to characterize tumor response and control in patients with unresectable stage III NSCLC treated with concurrent chemoradiotherapy followed by consolidation therapy with durvalumab (PRECISION): protocol for a prospective longitudinal biomarker study

BACKGROUND: Concurrent platinum-based chemoradiotherapy (CRT) followed by durvalumab maintenance treatment represents the new standard of care in unresectable stage III non-small cell lung cancer (NSCLC). In this prospective hypothesis-generating single-center study, we aim to identify a framework o...

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Detalles Bibliográficos
Autores principales: Käsmann, Lukas, Taugner, Julian, Eze, Chukwuka, Nieto, Alexander, Pelikan, Carolyn, Flörsch, Benedikt, Kenndoff, Saskia, Hofer, Thomas P., Nössner, Elfriede, Schulz, Christian, Unterrainer, Marcus, Tufman, Amanda, Klauschen, Frederick, Jung, Andreas, Neumann, Jens, Kumbrink, Jörg, Reinmuth, Niels, Bartenstein, Peter, Belka, Claus, Manapov, Farkhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359949/
https://www.ncbi.nlm.nih.gov/pubmed/35958344
http://dx.doi.org/10.21037/tlcr-21-1010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9359949/
https://www.ncbi.nlm.nih.gov/pubmed/35958344
http://dx.doi.org/10.21037/tlcr-21-1010

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