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Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru
The Central Andes of Peru are a region of great concern regarding pesticide risk to the health of local communities. Therefore, we conducted an observational study to assess the level of pesticide contamination among Andean people. Analytical chemistry methods were used to measure the concentrations...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360020/ https://www.ncbi.nlm.nih.gov/pubmed/35941193 http://dx.doi.org/10.1038/s41598-022-17772-1 |
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author | Honles, Jorge Clisson, Claire Monge, Claudia Vásquez-Ocmín, Pedro Cerapio, Juan Pablo Palamy, Sysay Casavilca-Zambrano, Sandro Herrera, Javier Pineau, Pascal Deharo, Eric Peynet, Vincent Bertani, Stéphane |
author_facet | Honles, Jorge Clisson, Claire Monge, Claudia Vásquez-Ocmín, Pedro Cerapio, Juan Pablo Palamy, Sysay Casavilca-Zambrano, Sandro Herrera, Javier Pineau, Pascal Deharo, Eric Peynet, Vincent Bertani, Stéphane |
author_sort | Honles, Jorge |
collection | PubMed |
description | The Central Andes of Peru are a region of great concern regarding pesticide risk to the health of local communities. Therefore, we conducted an observational study to assess the level of pesticide contamination among Andean people. Analytical chemistry methods were used to measure the concentrations of 170 pesticide-related compounds in hair samples from 50 adult Andean subjects living in rural and urban areas. As part of the study, a questionnaire was administered to the subjects to collect information regarding factors that increase the risk of pesticide exposure. Our results indicate that Andean people are strongly exposed to agrochemicals, being contaminated with a wide array of pesticide-related compounds at high concentration levels. Multivariate analyses and geostatistical modeling identified sociodemographic factors associated with rurality and food origin that increase pesticide exposure risk. The present study represents the first comprehensive investigation of pesticide-related compounds detected in body samples collected from people living in the Central Andes of Peru. Our findings pinpoint an alarming environmental situation that threatens human health in the region and provide a rationale for improving public policies to protect local communities. |
format | Online Article Text |
id | pubmed-9360020 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-93600202022-08-10 Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru Honles, Jorge Clisson, Claire Monge, Claudia Vásquez-Ocmín, Pedro Cerapio, Juan Pablo Palamy, Sysay Casavilca-Zambrano, Sandro Herrera, Javier Pineau, Pascal Deharo, Eric Peynet, Vincent Bertani, Stéphane Sci Rep Article The Central Andes of Peru are a region of great concern regarding pesticide risk to the health of local communities. Therefore, we conducted an observational study to assess the level of pesticide contamination among Andean people. Analytical chemistry methods were used to measure the concentrations of 170 pesticide-related compounds in hair samples from 50 adult Andean subjects living in rural and urban areas. As part of the study, a questionnaire was administered to the subjects to collect information regarding factors that increase the risk of pesticide exposure. Our results indicate that Andean people are strongly exposed to agrochemicals, being contaminated with a wide array of pesticide-related compounds at high concentration levels. Multivariate analyses and geostatistical modeling identified sociodemographic factors associated with rurality and food origin that increase pesticide exposure risk. The present study represents the first comprehensive investigation of pesticide-related compounds detected in body samples collected from people living in the Central Andes of Peru. Our findings pinpoint an alarming environmental situation that threatens human health in the region and provide a rationale for improving public policies to protect local communities. Nature Publishing Group UK 2022-08-08 /pmc/articles/PMC9360020/ /pubmed/35941193 http://dx.doi.org/10.1038/s41598-022-17772-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Honles, Jorge Clisson, Claire Monge, Claudia Vásquez-Ocmín, Pedro Cerapio, Juan Pablo Palamy, Sysay Casavilca-Zambrano, Sandro Herrera, Javier Pineau, Pascal Deharo, Eric Peynet, Vincent Bertani, Stéphane Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru |
title | Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru |
title_full | Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru |
title_fullStr | Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru |
title_full_unstemmed | Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru |
title_short | Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru |
title_sort | exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the central andes of peru |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360020/ https://www.ncbi.nlm.nih.gov/pubmed/35941193 http://dx.doi.org/10.1038/s41598-022-17772-1 |
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