Cooperation of Striatin 3 and MAP4K4 promotes growth and tissue invasion

MAP4K4 is associated with increased motility and reduced proliferation in tumor cells, but the regulation of this dichotomous functionality remained elusive. We find that MAP4K4 interacts with striatin 3 and 4 (STRN3/4) and that STRN3 and MAP4K4 exert opposing functions in Hippo signaling and clonal...

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Detalles Bibliográficos
Autores principales: Migliavacca, Jessica, Züllig, Buket, Capdeville, Charles, Grotzer, Michael A., Baumgartner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360036/
https://www.ncbi.nlm.nih.gov/pubmed/35941177
http://dx.doi.org/10.1038/s42003-022-03708-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360036/
https://www.ncbi.nlm.nih.gov/pubmed/35941177
http://dx.doi.org/10.1038/s42003-022-03708-y

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