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Cooperation of Striatin 3 and MAP4K4 promotes growth and tissue invasion
MAP4K4 is associated with increased motility and reduced proliferation in tumor cells, but the regulation of this dichotomous functionality remained elusive. We find that MAP4K4 interacts with striatin 3 and 4 (STRN3/4) and that STRN3 and MAP4K4 exert opposing functions in Hippo signaling and clonal...
Autores principales: | Migliavacca, Jessica, Züllig, Buket, Capdeville, Charles, Grotzer, Michael A., Baumgartner, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360036/ https://www.ncbi.nlm.nih.gov/pubmed/35941177 http://dx.doi.org/10.1038/s42003-022-03708-y |
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