GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy

Renal fibrosis is a common consequence of various progressive nephropathies, including obstructive nephropathy, and ultimately leads to kidney failure. Infiltration of inflammatory cells is a prominent feature of renal injury after draining blockages from the kidney, and correlates closely with the...

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Detalles Bibliográficos
Autores principales: Wang, Yujia, Li, Yinshuang, Chen, Zhimin, Yuan, Ying, Su, Qinglin, Ye, Keng, Chen, Caiming, Li, Guoping, Song, Yankun, Chen, Hong, Xu, Yanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360039/
https://www.ncbi.nlm.nih.gov/pubmed/35941120
http://dx.doi.org/10.1038/s41419-022-05138-4

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