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Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size

Cellular competition for limiting hematopoietic factors is a physiologically regulated but poorly understood process. Here, we studied this phenomenon by hampering hematopoietic progenitor access to Leptin receptor(+) mesenchymal stem/progenitor cells (MSPCs) and endothelial cells (ECs). We show tha...

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Detalles Bibliográficos
Autores principales: Miao, Runfeng, Chun, Harim, Feng, Xing, Gomes, Ana Cordeiro, Choi, Jungmin, Pereira, João P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360400/
https://www.ncbi.nlm.nih.gov/pubmed/35941168
http://dx.doi.org/10.1038/s41467-022-32228-w