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Alpha-cell paracrine signaling in the regulation of beta-cell insulin secretion

As an incretin hormone, glucagon-like peptide 1 (GLP-1) lowers blood glucose levels by enhancing glucose-stimulated insulin secretion from pancreatic beta-cells. Therapies targeting the GLP-1 receptor (GLP-1R) use the classical incretin model as a physiological framework in which GLP-1 secreted from...

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Detalles Bibliográficos
Autores principales:	Holter, Marlena M., Saikia, Mridusmita, Cummings, Bethany P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360487/ https://www.ncbi.nlm.nih.gov/pubmed/35957816 http://dx.doi.org/10.3389/fendo.2022.934775

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