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Noninvasive Ophthalmic Imaging Measures Retinal Degeneration and Vision Deficits in Ndufs4(−/−) Mouse Model of Mitochondrial Complex I Deficiency

PURPOSE: To characterize postnatal ocular pathology in a Ndufs4(−)(/)(−) mouse model of complex I deficiency using noninvasive retinal imaging and visual testing. METHODS: Ndufs4(−)(/)(−) mice and wild-type (WT) littermates were analyzed at 3, 5, and 7 weeks postnatal. Retinal morphology was visuali...

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Detalles Bibliográficos
Autores principales:	Avrutsky, Maria I., Lawson, Jacqueline M., Smart, Jade E., Chen, Claire W., Troy, Carol M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360534/ https://www.ncbi.nlm.nih.gov/pubmed/35921115 http://dx.doi.org/10.1167/tvst.11.8.5

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