Pan-caspase inhibition during normothermic machine perfusion of discarded livers mitigates ex situ innate immune responses

Access to liver transplantation is limited by a significant organ shortage. The recent introduction of machine perfusion technology allows surgeons to monitor and assess ex situ liver function prior to transplantation. However, many donated organs are of inadequate quality for transplant, though opp...

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Detalles Bibliográficos
Autores principales: Raigani, Siavash, Santiago, John, Ohman, Anders, Heaney, Megan, Baptista, Sofia, Coe, Taylor M., de Vries, Reinier J., Rosales, Ivy, Shih, Angela, Markmann, James F., Gruppuso, Philip, Uygun, Korkut, Sanders, Jennifer, Yeh, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360556/
https://www.ncbi.nlm.nih.gov/pubmed/35958587
http://dx.doi.org/10.3389/fimmu.2022.940094

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