Cargando…

Quercetin Alleviates Pulmonary Fibrosis in Mice Exposed to Silica by Inhibiting Macrophage Senescence

Quercetin exerts anti-inflammatory, anti-oxidant and other protective effects. Previous studies have shown that senescent cells, such as fibroblasts and type II airway epithelial cells, are strongly implicated in the development of pulmonary fibrosis pathology. However, the role of senescent macroph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geng, Fei, Xu, Mengying, Zhao, Lan, Zhang, Haoming, Li, Jiarui, Jin, Fuyu, Li, Yaqian, Li, Tian, Yang, Xinyu, Li, Shifeng, Gao, Xuemin, Cai, Wenchen, Mao, Na, Sun, Ying, Liu, Heliang, Xu, Hong, Wei, Zhongqiu, Yang, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360590/ https://www.ncbi.nlm.nih.gov/pubmed/35959439 http://dx.doi.org/10.3389/fphar.2022.912029

Ejemplares similares

Ac-SDKP Attenuates Activation of Lung Macrophages and Bone Osteoclasts in Rats Exposed to Silica by Inhibition of TLR4 and RANKL Signaling Pathways
por: Jin, Fuyu, et al.
Publicado: (2021)

Minute Cellular Nodules as Early Lesions in Rats with Silica Exposure via Inhalation
por: Li, Yaqian, et al.
Publicado: (2022)

Quercetin Alleviates Pulmonary Fibrosis in Silicotic Mice by Inhibiting Macrophage Transition and TGF-β-Smad2/3 Pathway
por: Geng, Fei, et al.
Publicado: (2023)

Thalidomide Alleviates Pulmonary Fibrosis Induced by Silica in Mice by Inhibiting ER Stress and the TLR4-NF-κB Pathway
por: Li, Yaqian, et al.
Publicado: (2022)

Pulmonary Silicosis Alters MicroRNA Expression in Rat Lung and miR-411-3p Exerts Anti-fibrotic Effects by Inhibiting MRTF-A/SRF Signaling
por: Gao, Xuemin, et al.
Publicado: (2020)

Inhibition of miR-155-5p Exerts Anti-Fibrotic Effects in Silicotic Mice by Regulating Meprin α
por: Chen, Yingying, et al.
Publicado: (2019)

MicroRNA‐411‐3p inhibits bleomycin‐induced skin fibrosis by regulating transforming growth factor‐β/Smad ubiquitin regulatory factor‐2 signalling
por: Zhang, Ziyan, et al.
Publicado: (2021)

Oxamate Attenuates Glycolysis and ER Stress in Silicotic Mice
por: Mao, Na, et al.
Publicado: (2022)

Effect of Sex Differences in Silicotic Mice
por: Jin, Fuyu, et al.
Publicado: (2022)

Glycolytic Reprogramming in Silica-Induced Lung Macrophages and Silicosis Reversed by Ac-SDKP Treatment
por: Mao, Na, et al.
Publicado: (2021)

Dasatinib Plus Quercetin Alleviates Choroid Neovascularization by Reducing the Cellular Senescence Burden in the RPE–Choroid
por: Wang, Yinhao, et al.
Publicado: (2023)

Silica Perturbs Primary Cilia and Causes Myofibroblast Differentiation during Silicosis by Reduction of the KIF3A-Repressor GLI3 Complex
por: Li, Shifeng, et al.
Publicado: (2020)

ACE2 Attenuates Epithelial-Mesenchymal Transition in MLE-12 Cells Induced by Silica
por: Li, Shumin, et al.
Publicado: (2020)

Reduction in Lens Epithelial Cell Senescence Burden through Dasatinib Plus Quercetin or Rapamycin Alleviates D-Galactose-Induced Cataract Progression
por: Wang, Yinhao, et al.
Publicado: (2022)

Transcriptomic analysis identifies upregulation of secreted phosphoprotein 1 in silicotic rats
por: Cai, Wenchen, et al.
Publicado: (2021)

Acetylated α-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica
por: Xiaojun, Wang, et al.
Publicado: (2016)

PH-Sensitive, Polymer Functionalized, Nonporous Silica Nanoparticles for Quercetin Controlled Release
por: Xu, Lin, et al.
Publicado: (2019)

Long-Term Administration of LL-37 Can Induce Irreversible Rosacea-like Lesion
por: Zhang, Chuanxi, et al.
Publicado: (2023)

Inhibition of Oncogenic Src Ameliorates Silica-Induced Pulmonary Fibrosis via PI3K/AKT Pathway
por: Hao, Xiaohui, et al.
Publicado: (2023)

Quercetin alleviates acute kidney injury by inhibiting ferroptosis
por: Wang, Yue, et al.
Publicado: (2020)

Effect of different exposed lights on quercetin and quercetin glucoside content in onion (Allium cepa L.)
por: Ko, Eun Young, et al.
Publicado: (2015)

Aging Resistance of Biocomposites Crosslinked with Silica and Quercetin
por: Masek, Anna, et al.
Publicado: (2021)

Early Identification, Accurate Diagnosis, and Treatment of Silicosis
por: Li, Tian, et al.
Publicado: (2022)

Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice
por: Yu, Yang, et al.
Publicado: (2013)

Interaction between autophagy and senescence is required for dihydroartemisinin to alleviate liver fibrosis
por: Zhang, Zili, et al.
Publicado: (2017)

Quercetin Alleviates Ferroptosis of Pancreatic β Cells in Type 2 Diabetes
por: Li, Dan, et al.
Publicado: (2020)

Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity
por: Fan, Hui-Ran, et al.
Publicado: (2018)

Dibutyryl-cAMP attenuates pulmonary fibrosis by blocking myofibroblast differentiation via PKA/CREB/CBP signaling in rats with silicosis
por: Liu, Yan, et al.
Publicado: (2017)

Danggui-Buxue decoction alleviated vascular senescence in mice exposed to chronic intermittent hypoxia through activating the Nrf2/HO-1 pathway
por: Li, Dongli, et al.
Publicado: (2023)

Hydrogenation of Toluene to Methyl Cyclohexane over PtRh Bimetallic Nanoparticle-Encaged Hollow Mesoporous Silica Catalytic Nanoreactors
por: Li, Kaijie, et al.
Publicado: (2021)

Self-Healable Biocomposites Crosslinked with a Combination of Silica and Quercetin
por: Olejnik, Olga, et al.
Publicado: (2021)

Quercetin alleviates pulmonary angiogenesis in a rat model of hepatopulmonary syndrome
por: Li, X., et al.
Publicado: (2016)

Quercetin alleviates lipopolysaccharide-induced acute lung injury by inhibiting ferroptosis via the Sirt1/Nrf2/Gpx4 pathway
por: Deng, Shihua, et al.
Publicado: (2023)

Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence
por: Jiang, Yue-Hua, et al.
Publicado: (2020)

iPSC-sEVs alleviate microglia senescence to protect against ischemic stroke in aged mice
por: Niu, Xinyu, et al.
Publicado: (2023)

Heparin coated meta-organic framework co-delivering doxorubicin and quercetin for effective chemotherapy of lung carcinoma
por: Sun, Xiaojun, et al.
Publicado: (2020)

Quercetin alleviates generalized hyperalgesia in mice with induced adenomyosis
por: Nie, Jichan, et al.
Publicado: (2017)

Down-regulation of ZNF252P-AS1 alleviates ovarian cancer progression by binding miR-324-3p to downregulate LY6K
por: Geng, Li, et al.
Publicado: (2022)

Bmi-1 alleviates adventitial fibroblast senescence by eliminating ROS in pulmonary hypertension
por: Li, Kai, et al.
Publicado: (2021)

Silica/quercetin sol–gel hybrids as antioxidant dental implant materials
por: Catauro, Michelina, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6diq3gtis6pv1t8po12c51455l