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Atypical CT findings of renal neuroblastoma: a case report
BACKGROUND: The neuroblastoma (NB) is a highly malignant tumor of the ectoderm of sympathetic nerve cells and one of the most common malignant tumors in children, which can occur in any part of the sympathetic nerve plexus distribution, however it is less common in the kidney. CASE DESCRIPTION: Here...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360815/ https://www.ncbi.nlm.nih.gov/pubmed/35958006 http://dx.doi.org/10.21037/tp-22-205 |
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author | Jiang, Maoyan Hu, Xianwen Qian, Kai Yang, Peiqing Tang, Yang Wang, Pan Cai, Jiong |
author_facet | Jiang, Maoyan Hu, Xianwen Qian, Kai Yang, Peiqing Tang, Yang Wang, Pan Cai, Jiong |
author_sort | Jiang, Maoyan |
collection | PubMed |
description | BACKGROUND: The neuroblastoma (NB) is a highly malignant tumor of the ectoderm of sympathetic nerve cells and one of the most common malignant tumors in children, which can occur in any part of the sympathetic nerve plexus distribution, however it is less common in the kidney. CASE DESCRIPTION: Here we present a case of a 4-year-old boy who came to our hospital for medical help because of “abdominal distension for 1 day”. Abdominal computed tomography (CT) revealed a huge retroperitoneal soft tissue mass with unclear boundaries with kidneys and adrenal glands, and low-density cystic necrosis areas were seen in the tumor. Contrast-enhanced scan showed that the mass showed mild heterogeneous enhancement. Based on these findings in the patient, he was initially considered to have Wilms tumor, but was finally pathologically confirmed as renal NB. The purpose of this article is to provide the clinicopathological features and CT manifestations of renal NB, and to discuss its differential diagnosis with other renal tumors, in order to better provide clinicians with a better understanding of the rare solid tumor. The renal NB is usually a large lobulated soft tissue mass with unclear boundary and incomplete capsule, which is prone to hemorrhage, necrosis, cystic degeneration and calcification. On CT, the mass is usually isodensity or slightly hypodense, and the cystic degeneration and necrosis area is hypodense, and on contrast-enhanced scan, it can be mildly to significantly enhanced, but the cystic degeneration and necrosis area have no enhancement. CONCLUSIONS: The CT findings of our case were atypical and overlapped with those of Wilms, so our case suggests that renal NB should be considered as one of the differential diagnoses of Wilms, the most common malignancy of the kidney in children. |
format | Online Article Text |
id | pubmed-9360815 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-93608152022-08-10 Atypical CT findings of renal neuroblastoma: a case report Jiang, Maoyan Hu, Xianwen Qian, Kai Yang, Peiqing Tang, Yang Wang, Pan Cai, Jiong Transl Pediatr Case Report BACKGROUND: The neuroblastoma (NB) is a highly malignant tumor of the ectoderm of sympathetic nerve cells and one of the most common malignant tumors in children, which can occur in any part of the sympathetic nerve plexus distribution, however it is less common in the kidney. CASE DESCRIPTION: Here we present a case of a 4-year-old boy who came to our hospital for medical help because of “abdominal distension for 1 day”. Abdominal computed tomography (CT) revealed a huge retroperitoneal soft tissue mass with unclear boundaries with kidneys and adrenal glands, and low-density cystic necrosis areas were seen in the tumor. Contrast-enhanced scan showed that the mass showed mild heterogeneous enhancement. Based on these findings in the patient, he was initially considered to have Wilms tumor, but was finally pathologically confirmed as renal NB. The purpose of this article is to provide the clinicopathological features and CT manifestations of renal NB, and to discuss its differential diagnosis with other renal tumors, in order to better provide clinicians with a better understanding of the rare solid tumor. The renal NB is usually a large lobulated soft tissue mass with unclear boundary and incomplete capsule, which is prone to hemorrhage, necrosis, cystic degeneration and calcification. On CT, the mass is usually isodensity or slightly hypodense, and the cystic degeneration and necrosis area is hypodense, and on contrast-enhanced scan, it can be mildly to significantly enhanced, but the cystic degeneration and necrosis area have no enhancement. CONCLUSIONS: The CT findings of our case were atypical and overlapped with those of Wilms, so our case suggests that renal NB should be considered as one of the differential diagnoses of Wilms, the most common malignancy of the kidney in children. AME Publishing Company 2022-07 /pmc/articles/PMC9360815/ /pubmed/35958006 http://dx.doi.org/10.21037/tp-22-205 Text en 2022 Translational Pediatrics. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Case Report Jiang, Maoyan Hu, Xianwen Qian, Kai Yang, Peiqing Tang, Yang Wang, Pan Cai, Jiong Atypical CT findings of renal neuroblastoma: a case report |
title | Atypical CT findings of renal neuroblastoma: a case report |
title_full | Atypical CT findings of renal neuroblastoma: a case report |
title_fullStr | Atypical CT findings of renal neuroblastoma: a case report |
title_full_unstemmed | Atypical CT findings of renal neuroblastoma: a case report |
title_short | Atypical CT findings of renal neuroblastoma: a case report |
title_sort | atypical ct findings of renal neuroblastoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360815/ https://www.ncbi.nlm.nih.gov/pubmed/35958006 http://dx.doi.org/10.21037/tp-22-205 |
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