Cargando…

Atypical CT findings of renal neuroblastoma: a case report

BACKGROUND: The neuroblastoma (NB) is a highly malignant tumor of the ectoderm of sympathetic nerve cells and one of the most common malignant tumors in children, which can occur in any part of the sympathetic nerve plexus distribution, however it is less common in the kidney. CASE DESCRIPTION: Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Maoyan, Hu, Xianwen, Qian, Kai, Yang, Peiqing, Tang, Yang, Wang, Pan, Cai, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360815/
https://www.ncbi.nlm.nih.gov/pubmed/35958006
http://dx.doi.org/10.21037/tp-22-205
_version_ 1784764408387338240
author Jiang, Maoyan
Hu, Xianwen
Qian, Kai
Yang, Peiqing
Tang, Yang
Wang, Pan
Cai, Jiong
author_facet Jiang, Maoyan
Hu, Xianwen
Qian, Kai
Yang, Peiqing
Tang, Yang
Wang, Pan
Cai, Jiong
author_sort Jiang, Maoyan
collection PubMed
description BACKGROUND: The neuroblastoma (NB) is a highly malignant tumor of the ectoderm of sympathetic nerve cells and one of the most common malignant tumors in children, which can occur in any part of the sympathetic nerve plexus distribution, however it is less common in the kidney. CASE DESCRIPTION: Here we present a case of a 4-year-old boy who came to our hospital for medical help because of “abdominal distension for 1 day”. Abdominal computed tomography (CT) revealed a huge retroperitoneal soft tissue mass with unclear boundaries with kidneys and adrenal glands, and low-density cystic necrosis areas were seen in the tumor. Contrast-enhanced scan showed that the mass showed mild heterogeneous enhancement. Based on these findings in the patient, he was initially considered to have Wilms tumor, but was finally pathologically confirmed as renal NB. The purpose of this article is to provide the clinicopathological features and CT manifestations of renal NB, and to discuss its differential diagnosis with other renal tumors, in order to better provide clinicians with a better understanding of the rare solid tumor. The renal NB is usually a large lobulated soft tissue mass with unclear boundary and incomplete capsule, which is prone to hemorrhage, necrosis, cystic degeneration and calcification. On CT, the mass is usually isodensity or slightly hypodense, and the cystic degeneration and necrosis area is hypodense, and on contrast-enhanced scan, it can be mildly to significantly enhanced, but the cystic degeneration and necrosis area have no enhancement. CONCLUSIONS: The CT findings of our case were atypical and overlapped with those of Wilms, so our case suggests that renal NB should be considered as one of the differential diagnoses of Wilms, the most common malignancy of the kidney in children.
format Online
Article
Text
id pubmed-9360815
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher AME Publishing Company
record_format MEDLINE/PubMed
spelling pubmed-93608152022-08-10 Atypical CT findings of renal neuroblastoma: a case report Jiang, Maoyan Hu, Xianwen Qian, Kai Yang, Peiqing Tang, Yang Wang, Pan Cai, Jiong Transl Pediatr Case Report BACKGROUND: The neuroblastoma (NB) is a highly malignant tumor of the ectoderm of sympathetic nerve cells and one of the most common malignant tumors in children, which can occur in any part of the sympathetic nerve plexus distribution, however it is less common in the kidney. CASE DESCRIPTION: Here we present a case of a 4-year-old boy who came to our hospital for medical help because of “abdominal distension for 1 day”. Abdominal computed tomography (CT) revealed a huge retroperitoneal soft tissue mass with unclear boundaries with kidneys and adrenal glands, and low-density cystic necrosis areas were seen in the tumor. Contrast-enhanced scan showed that the mass showed mild heterogeneous enhancement. Based on these findings in the patient, he was initially considered to have Wilms tumor, but was finally pathologically confirmed as renal NB. The purpose of this article is to provide the clinicopathological features and CT manifestations of renal NB, and to discuss its differential diagnosis with other renal tumors, in order to better provide clinicians with a better understanding of the rare solid tumor. The renal NB is usually a large lobulated soft tissue mass with unclear boundary and incomplete capsule, which is prone to hemorrhage, necrosis, cystic degeneration and calcification. On CT, the mass is usually isodensity or slightly hypodense, and the cystic degeneration and necrosis area is hypodense, and on contrast-enhanced scan, it can be mildly to significantly enhanced, but the cystic degeneration and necrosis area have no enhancement. CONCLUSIONS: The CT findings of our case were atypical and overlapped with those of Wilms, so our case suggests that renal NB should be considered as one of the differential diagnoses of Wilms, the most common malignancy of the kidney in children. AME Publishing Company 2022-07 /pmc/articles/PMC9360815/ /pubmed/35958006 http://dx.doi.org/10.21037/tp-22-205 Text en 2022 Translational Pediatrics. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Case Report
Jiang, Maoyan
Hu, Xianwen
Qian, Kai
Yang, Peiqing
Tang, Yang
Wang, Pan
Cai, Jiong
Atypical CT findings of renal neuroblastoma: a case report
title Atypical CT findings of renal neuroblastoma: a case report
title_full Atypical CT findings of renal neuroblastoma: a case report
title_fullStr Atypical CT findings of renal neuroblastoma: a case report
title_full_unstemmed Atypical CT findings of renal neuroblastoma: a case report
title_short Atypical CT findings of renal neuroblastoma: a case report
title_sort atypical ct findings of renal neuroblastoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9360815/
https://www.ncbi.nlm.nih.gov/pubmed/35958006
http://dx.doi.org/10.21037/tp-22-205
work_keys_str_mv AT jiangmaoyan atypicalctfindingsofrenalneuroblastomaacasereport
AT huxianwen atypicalctfindingsofrenalneuroblastomaacasereport
AT qiankai atypicalctfindingsofrenalneuroblastomaacasereport
AT yangpeiqing atypicalctfindingsofrenalneuroblastomaacasereport
AT tangyang atypicalctfindingsofrenalneuroblastomaacasereport
AT wangpan atypicalctfindingsofrenalneuroblastomaacasereport
AT caijiong atypicalctfindingsofrenalneuroblastomaacasereport