Cargando…

Stemness Analysis Uncovers That The Peroxisome Proliferator-Activated Receptor Signaling Pathway Can Mediate Fatty Acid Homeostasis In Sorafenib-Resistant Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) stem cells are regarded as an important part of individualized HCC treatment and sorafenib resistance. However, there is lacking systematic assessment of stem-like indices and associations with a response of sorafenib in HCC. Our study thus aimed to evaluate the status...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Tingze, Wu, Tianzhi, Zhang, Yanxia, Zhou, Lang, Liu, Shanshan, Li, Lin, Li, Ming, Hu, Erqiang, Wang, Qianwen, Fu, Xiaocong, Zhan, Li, Xie, Zijing, Xie, Wenqin, Huang, Xianying, Shang, Xuan, Yu, Guangchuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361019/ https://www.ncbi.nlm.nih.gov/pubmed/35957896 http://dx.doi.org/10.3389/fonc.2022.912694

Ejemplares similares

MicrobiotaProcess: A comprehensive R package for deep mining microbiome
por: Xu, Shuangbin, et al.
Publicado: (2023)

clusterProfiler 4.0: A universal enrichment tool for interpreting omics data
por: Wu, Tianzhi, et al.
Publicado: (2021)

ggtreeExtra: Compact Visualization of Richly Annotated Phylogenetic Data
por: Xu, Shuangbin, et al.
Publicado: (2021)

nCov2019: an R package for studying the COVID-19 coronavirus pandemic
por: Wu, Tianzhi, et al.
Publicado: (2021)

Use ggbreak to Effectively Utilize Plotting Space to Deal With Large Datasets and Outliers
por: Xu, Shuangbin, et al.
Publicado: (2021)

Identification of Prognostic Stromal-Immune Score–Based Genes in Hepatocellular Carcinoma Microenvironment
por: Liu, Shanshan, et al.
Publicado: (2021)

Redox regulated peroxisome homeostasis
por: Wang, Xiaofeng, et al.
Publicado: (2014)

Characterization of toxin-antitoxin systems from public sequencing data: A case study in Pseudomonas aeruginosa
por: Dai, Zehan, et al.
Publicado: (2022)

Glutathione and peroxisome redox homeostasis
por: Ferreira, Maria J., et al.
Publicado: (2023)

VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis
por: Hua, Rong, et al.
Publicado: (2017)

Peroxisomal regulation of redox homeostasis and adipocyte metabolism
por: Liu, Jingjing, et al.
Publicado: (2019)

Dynamics of Peroxisome Homeostasis and Its Role in Stress Response and Signaling in Plants
por: Su, Tong, et al.
Publicado: (2019)

Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay
por: Rosenthal, Mira, et al.
Publicado: (2020)

Yeast Methylotrophy: Metabolism, Gene Regulation and Peroxisome Homeostasis
por: Yurimoto, Hiroya, et al.
Publicado: (2011)

Editorial: Biomedical Data Visualization: Methods and Applications
por: Wu, Tianzhi, et al.
Publicado: (2022)

MMINP: A computational framework of microbe-metabolite interactions-based metabolic profiles predictor based on the O2-PLS algorithm
por: Tang, Wenli, et al.
Publicado: (2023)

Functional Analysis of GSTK1 in Peroxisomal Redox Homeostasis in HEK-293 Cells
por: Costa, Cláudio F., et al.
Publicado: (2023)

Using Co-Expression Analysis and Stress-Based Screens to Uncover Arabidopsis Peroxisomal Proteins Involved in Drought Response
por: Li, Jiying, et al.
Publicado: (2015)

GHR knockdown enhances the sensitivity of HCC cells to sorafenib
por: Gao, Shuang, et al.
Publicado: (2020)

Hepatic lipid homeostasis by peroxisome proliferator-activated receptor gamma 2()
por: Lee, Yoon Kwang, et al.
Publicado: (2018)

Peroxisomal Stress Response and Inter-Organelle Communication in Cellular Homeostasis and Aging
por: Kim, Jinoh, et al.
Publicado: (2022)

Peroxisomal regulation of energy homeostasis: Effect on obesity and related metabolic disorders
por: Kleiboeker, Brian, et al.
Publicado: (2022)

Regulation of Peroxisome Homeostasis by Post-Translational Modification in the Methylotrophic Yeast Komagataella phaffii
por: Ohsawa, Shin, et al.
Publicado: (2022)

PEX11 promotes peroxisome division independently of peroxisome metabolism
por: Li, Xiaoling, et al.
Publicado: (2002)

Peroxisomes contribute to reactive oxygen species homeostasis and cell division induction in Arabidopsis protoplasts
por: Tiew, Terence W.-Y., et al.
Publicado: (2015)

Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis
por: Hofer, Dina C., et al.
Publicado: (2017)

Insights into the Structure and Function of the Pex1/Pex6 AAA-ATPase in Peroxisome Homeostasis
por: Judy, Ryan M., et al.
Publicado: (2022)

The mammalian peroxisomal membrane is permeable to both GSH and GSSG – Implications for intraperoxisomal redox homeostasis
por: Ferreira, Maria J., et al.
Publicado: (2023)

TMEM135 links peroxisomes to the regulation of brown fat mitochondrial fission and energy homeostasis
por: Hu, Donghua, et al.
Publicado: (2023)

Hydrogen sulfide: a gaseous signaling molecule modulates tissue homeostasis: implications in ophthalmic diseases
por: Han, Yuyi, et al.
Publicado: (2019)

Efficacy of sorafenib in patients with hepatocellular carcinoma after resection: a meta-analysis
por: Shang, Jin, et al.
Publicado: (2017)

Challenging muscle homeostasis uncovers novel chaperone interactions in Caenorhabditis elegans
por: Frumkin, Anna, et al.
Publicado: (2014)

Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis Throughout the Day
por: Malik, Dania M., et al.
Publicado: (2023)

Peroxisome Synthesis in the Absence of Preexisting Peroxisomes
por: South, Sarah T., et al.
Publicado: (1999)

TNF-α is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma
por: Tan, Wenliang, et al.
Publicado: (2018)

Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism
por: Landowski, Michael, et al.
Publicado: (2023)

Myeloid-derived suppressor cells promote tumor growth and sorafenib resistance by inducing FGF1 upregulation and fibrosis
por: Deng, Xue, et al.
Publicado: (2022)

Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Energy Homeostasis of Dairy Animals: Exploiting Their Modulation through Nutrigenomic Interventions
por: Hassan, Faiz-ul, et al.
Publicado: (2021)

AG-1024 Sensitizes Sorafenib-Resistant Hepatocellular Carcinoma Cells to Sorafenib via Enhancing G1/S Arrest
por: Zhou, Wei, et al.
Publicado: (2021)

Pilot Study of the Biological Properties and Vascularization of 3D Printed Bilayer Skin Grafts
por: Huyan, Yige, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h9r01ebooo3ne7c96qmk7aa8pc