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LncRNA GAS5 Knockdown Mitigates Hepatic Lipid Accumulation via Regulating MiR-26a-5p/PDE4B to Activate cAMP/CREB Pathway

OBJECTIVE: Non-alcoholic fatty liver disease (NAFLD) can be attributed to the dysregulation of hepatic lipid metabolism; however, its cellular and molecular mechanisms remain unclear. This study aims to explore the effect of long non-coding RNA growth arrest specific 5 (GAS5) on hepatic lipid metabo...

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Detalles Bibliográficos
Autores principales: Xu, Shizan, Wang, Yajie, Li, Zhengyang, Hua, Qian, Jiang, Miao, Fan, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361042/
https://www.ncbi.nlm.nih.gov/pubmed/35957809
http://dx.doi.org/10.3389/fendo.2022.889858

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