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Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods

OBJECTIVE: Interstitial lung disease is the most frequent lung symptom of rheumatoid arthritis and is a significant contributor to morbidity. As a result, the target of this research was to measure the frequency of radiological and functional abnormalities in rheumatoid arthritis patients who did no...

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Autores principales: Wagih Abdelwahab, Heba, Shalabi, Nesrein M., Mohamed Rashad Ghoneim, Mahitab, Saad Farrag, Nesrine, Hamdy, Fatma, Elhoseiny, Fatma, Elmetwally Ali, Raed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Turkish Thoracic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361088/
https://www.ncbi.nlm.nih.gov/pubmed/35848433
http://dx.doi.org/10.5152/TurkThoracJ.2022.21263
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author Wagih Abdelwahab, Heba
Shalabi, Nesrein M.
Mohamed Rashad Ghoneim, Mahitab
Saad Farrag, Nesrine
Hamdy, Fatma
Elhoseiny, Fatma
Elmetwally Ali, Raed
author_facet Wagih Abdelwahab, Heba
Shalabi, Nesrein M.
Mohamed Rashad Ghoneim, Mahitab
Saad Farrag, Nesrine
Hamdy, Fatma
Elhoseiny, Fatma
Elmetwally Ali, Raed
author_sort Wagih Abdelwahab, Heba
collection PubMed
description OBJECTIVE: Interstitial lung disease is the most frequent lung symptom of rheumatoid arthritis and is a significant contributor to morbidity. As a result, the target of this research was to measure the frequency of radiological and functional abnormalities in rheumatoid arthritis patients who did not have any respiratory symptoms. MATERIAL AND METHODS: This study consists of 30 patients diagnosed with rheumatoid arthritis. All involved cases were exposed to entire history taking and clinical examination. All patients were examined by high-resolution computed tomography and pulmonary function tests. RESULTS: According to the computed tomography visual score, 73.3% showed interstitial lung disease. The most common abnormalities were reticular patterns (46.7%) followed by nodular patterns (40%) and septal lines (23.3%). However, 36% of the patients had a normal pulmonary function, while 32% had a small airway affection, 20% had restrictive lung disease, and 12% had obstructive lung disease. A significant association was found between supine expiratory volume and computed tomography visual score. Results showed no association between interstitial lung disease and all lung function test parameters. CONCLUSION: Subclinical interstitial lung disease is frequent among rheumatoid arthritis patents. A combination of pulmonary function tests with computed tomography is essential to enhance the recognition of subclinical interstitial lung disease as normal pulmonary function alone cannot exclude its presence.
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spelling pubmed-93610882022-08-15 Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods Wagih Abdelwahab, Heba Shalabi, Nesrein M. Mohamed Rashad Ghoneim, Mahitab Saad Farrag, Nesrine Hamdy, Fatma Elhoseiny, Fatma Elmetwally Ali, Raed Turk Thorac J Original Article OBJECTIVE: Interstitial lung disease is the most frequent lung symptom of rheumatoid arthritis and is a significant contributor to morbidity. As a result, the target of this research was to measure the frequency of radiological and functional abnormalities in rheumatoid arthritis patients who did not have any respiratory symptoms. MATERIAL AND METHODS: This study consists of 30 patients diagnosed with rheumatoid arthritis. All involved cases were exposed to entire history taking and clinical examination. All patients were examined by high-resolution computed tomography and pulmonary function tests. RESULTS: According to the computed tomography visual score, 73.3% showed interstitial lung disease. The most common abnormalities were reticular patterns (46.7%) followed by nodular patterns (40%) and septal lines (23.3%). However, 36% of the patients had a normal pulmonary function, while 32% had a small airway affection, 20% had restrictive lung disease, and 12% had obstructive lung disease. A significant association was found between supine expiratory volume and computed tomography visual score. Results showed no association between interstitial lung disease and all lung function test parameters. CONCLUSION: Subclinical interstitial lung disease is frequent among rheumatoid arthritis patents. A combination of pulmonary function tests with computed tomography is essential to enhance the recognition of subclinical interstitial lung disease as normal pulmonary function alone cannot exclude its presence. Turkish Thoracic Society 2022-07-01 /pmc/articles/PMC9361088/ /pubmed/35848433 http://dx.doi.org/10.5152/TurkThoracJ.2022.21263 Text en Turkish Thoracic Society https://creativecommons.org/licenses/by-nc/4.0/ Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Original Article
Wagih Abdelwahab, Heba
Shalabi, Nesrein M.
Mohamed Rashad Ghoneim, Mahitab
Saad Farrag, Nesrine
Hamdy, Fatma
Elhoseiny, Fatma
Elmetwally Ali, Raed
Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods
title Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods
title_full Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods
title_fullStr Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods
title_full_unstemmed Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods
title_short Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods
title_sort screening for subclinical interstitial lung disease in rheumatoid arthritis patients: functional and radiological methods
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361088/
https://www.ncbi.nlm.nih.gov/pubmed/35848433
http://dx.doi.org/10.5152/TurkThoracJ.2022.21263
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