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Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods
OBJECTIVE: Interstitial lung disease is the most frequent lung symptom of rheumatoid arthritis and is a significant contributor to morbidity. As a result, the target of this research was to measure the frequency of radiological and functional abnormalities in rheumatoid arthritis patients who did no...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Turkish Thoracic Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361088/ https://www.ncbi.nlm.nih.gov/pubmed/35848433 http://dx.doi.org/10.5152/TurkThoracJ.2022.21263 |
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author | Wagih Abdelwahab, Heba Shalabi, Nesrein M. Mohamed Rashad Ghoneim, Mahitab Saad Farrag, Nesrine Hamdy, Fatma Elhoseiny, Fatma Elmetwally Ali, Raed |
author_facet | Wagih Abdelwahab, Heba Shalabi, Nesrein M. Mohamed Rashad Ghoneim, Mahitab Saad Farrag, Nesrine Hamdy, Fatma Elhoseiny, Fatma Elmetwally Ali, Raed |
author_sort | Wagih Abdelwahab, Heba |
collection | PubMed |
description | OBJECTIVE: Interstitial lung disease is the most frequent lung symptom of rheumatoid arthritis and is a significant contributor to morbidity. As a result, the target of this research was to measure the frequency of radiological and functional abnormalities in rheumatoid arthritis patients who did not have any respiratory symptoms. MATERIAL AND METHODS: This study consists of 30 patients diagnosed with rheumatoid arthritis. All involved cases were exposed to entire history taking and clinical examination. All patients were examined by high-resolution computed tomography and pulmonary function tests. RESULTS: According to the computed tomography visual score, 73.3% showed interstitial lung disease. The most common abnormalities were reticular patterns (46.7%) followed by nodular patterns (40%) and septal lines (23.3%). However, 36% of the patients had a normal pulmonary function, while 32% had a small airway affection, 20% had restrictive lung disease, and 12% had obstructive lung disease. A significant association was found between supine expiratory volume and computed tomography visual score. Results showed no association between interstitial lung disease and all lung function test parameters. CONCLUSION: Subclinical interstitial lung disease is frequent among rheumatoid arthritis patents. A combination of pulmonary function tests with computed tomography is essential to enhance the recognition of subclinical interstitial lung disease as normal pulmonary function alone cannot exclude its presence. |
format | Online Article Text |
id | pubmed-9361088 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Turkish Thoracic Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-93610882022-08-15 Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods Wagih Abdelwahab, Heba Shalabi, Nesrein M. Mohamed Rashad Ghoneim, Mahitab Saad Farrag, Nesrine Hamdy, Fatma Elhoseiny, Fatma Elmetwally Ali, Raed Turk Thorac J Original Article OBJECTIVE: Interstitial lung disease is the most frequent lung symptom of rheumatoid arthritis and is a significant contributor to morbidity. As a result, the target of this research was to measure the frequency of radiological and functional abnormalities in rheumatoid arthritis patients who did not have any respiratory symptoms. MATERIAL AND METHODS: This study consists of 30 patients diagnosed with rheumatoid arthritis. All involved cases were exposed to entire history taking and clinical examination. All patients were examined by high-resolution computed tomography and pulmonary function tests. RESULTS: According to the computed tomography visual score, 73.3% showed interstitial lung disease. The most common abnormalities were reticular patterns (46.7%) followed by nodular patterns (40%) and septal lines (23.3%). However, 36% of the patients had a normal pulmonary function, while 32% had a small airway affection, 20% had restrictive lung disease, and 12% had obstructive lung disease. A significant association was found between supine expiratory volume and computed tomography visual score. Results showed no association between interstitial lung disease and all lung function test parameters. CONCLUSION: Subclinical interstitial lung disease is frequent among rheumatoid arthritis patents. A combination of pulmonary function tests with computed tomography is essential to enhance the recognition of subclinical interstitial lung disease as normal pulmonary function alone cannot exclude its presence. Turkish Thoracic Society 2022-07-01 /pmc/articles/PMC9361088/ /pubmed/35848433 http://dx.doi.org/10.5152/TurkThoracJ.2022.21263 Text en Turkish Thoracic Society https://creativecommons.org/licenses/by-nc/4.0/ Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Original Article Wagih Abdelwahab, Heba Shalabi, Nesrein M. Mohamed Rashad Ghoneim, Mahitab Saad Farrag, Nesrine Hamdy, Fatma Elhoseiny, Fatma Elmetwally Ali, Raed Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods |
title | Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods |
title_full | Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods |
title_fullStr | Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods |
title_full_unstemmed | Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods |
title_short | Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods |
title_sort | screening for subclinical interstitial lung disease in rheumatoid arthritis patients: functional and radiological methods |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361088/ https://www.ncbi.nlm.nih.gov/pubmed/35848433 http://dx.doi.org/10.5152/TurkThoracJ.2022.21263 |
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