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Synthesis and crystal structure of 1,3-bis­{[N,N-bis­(2-hy­droxy­eth­yl)amino]­meth­yl}-5-{[(4,6-di­methyl­pyridin-2-yl)amino]­meth­yl}-2,4,6-tri­ethyl­benzene

In the crystal structure of the title compound, C(30)H(50)N(4)O(4), the two bis­(hy­droxy­eth­yl)amino moieties and the 2,4-di­methyl­pyridinyl­amino unit of the mol­ecule are located on one side of the central benzene ring, while the ethyl substituents are oriented in the opposite direction. The di...

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Autores principales: Stapf, Manuel, Schmidt, Ute, Seichter, Wilhelm, Mazik, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361370/
https://www.ncbi.nlm.nih.gov/pubmed/35974834
http://dx.doi.org/10.1107/S2056989022007411
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author Stapf, Manuel
Schmidt, Ute
Seichter, Wilhelm
Mazik, Monika
author_facet Stapf, Manuel
Schmidt, Ute
Seichter, Wilhelm
Mazik, Monika
author_sort Stapf, Manuel
collection PubMed
description In the crystal structure of the title compound, C(30)H(50)N(4)O(4), the two bis­(hy­droxy­eth­yl)amino moieties and the 2,4-di­methyl­pyridinyl­amino unit of the mol­ecule are located on one side of the central benzene ring, while the ethyl substituents are oriented in the opposite direction. The dihedral angle between the planes of the aromatic rings is 73.6 (1)°. The conformation of the mol­ecule is stabilized by intra­molecular O—H⋯O (1.86–2.12 Å) and C—H⋯N (2.40, 2.54 Å) hydrogen bonds. Dimers of inversion-related mol­ecules represent the basic supra­molecular entities of the crystal structure. They are further connected via O—H⋯O hydrogen bonding into undulating layers extending parallel to the crystallographic bc plane. Inter­layer inter­action is accomplished by weak C—H⋯π contacts.
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spelling pubmed-93613702022-08-15 Synthesis and crystal structure of 1,3-bis­{[N,N-bis­(2-hy­droxy­eth­yl)amino]­meth­yl}-5-{[(4,6-di­methyl­pyridin-2-yl)amino]­meth­yl}-2,4,6-tri­ethyl­benzene Stapf, Manuel Schmidt, Ute Seichter, Wilhelm Mazik, Monika Acta Crystallogr E Crystallogr Commun Research Communications In the crystal structure of the title compound, C(30)H(50)N(4)O(4), the two bis­(hy­droxy­eth­yl)amino moieties and the 2,4-di­methyl­pyridinyl­amino unit of the mol­ecule are located on one side of the central benzene ring, while the ethyl substituents are oriented in the opposite direction. The dihedral angle between the planes of the aromatic rings is 73.6 (1)°. The conformation of the mol­ecule is stabilized by intra­molecular O—H⋯O (1.86–2.12 Å) and C—H⋯N (2.40, 2.54 Å) hydrogen bonds. Dimers of inversion-related mol­ecules represent the basic supra­molecular entities of the crystal structure. They are further connected via O—H⋯O hydrogen bonding into undulating layers extending parallel to the crystallographic bc plane. Inter­layer inter­action is accomplished by weak C—H⋯π contacts. International Union of Crystallography 2022-07-26 /pmc/articles/PMC9361370/ /pubmed/35974834 http://dx.doi.org/10.1107/S2056989022007411 Text en © Stapf et al. 2022 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Stapf, Manuel
Schmidt, Ute
Seichter, Wilhelm
Mazik, Monika
Synthesis and crystal structure of 1,3-bis­{[N,N-bis­(2-hy­droxy­eth­yl)amino]­meth­yl}-5-{[(4,6-di­methyl­pyridin-2-yl)amino]­meth­yl}-2,4,6-tri­ethyl­benzene
title Synthesis and crystal structure of 1,3-bis­{[N,N-bis­(2-hy­droxy­eth­yl)amino]­meth­yl}-5-{[(4,6-di­methyl­pyridin-2-yl)amino]­meth­yl}-2,4,6-tri­ethyl­benzene
title_full Synthesis and crystal structure of 1,3-bis­{[N,N-bis­(2-hy­droxy­eth­yl)amino]­meth­yl}-5-{[(4,6-di­methyl­pyridin-2-yl)amino]­meth­yl}-2,4,6-tri­ethyl­benzene
title_fullStr Synthesis and crystal structure of 1,3-bis­{[N,N-bis­(2-hy­droxy­eth­yl)amino]­meth­yl}-5-{[(4,6-di­methyl­pyridin-2-yl)amino]­meth­yl}-2,4,6-tri­ethyl­benzene
title_full_unstemmed Synthesis and crystal structure of 1,3-bis­{[N,N-bis­(2-hy­droxy­eth­yl)amino]­meth­yl}-5-{[(4,6-di­methyl­pyridin-2-yl)amino]­meth­yl}-2,4,6-tri­ethyl­benzene
title_short Synthesis and crystal structure of 1,3-bis­{[N,N-bis­(2-hy­droxy­eth­yl)amino]­meth­yl}-5-{[(4,6-di­methyl­pyridin-2-yl)amino]­meth­yl}-2,4,6-tri­ethyl­benzene
title_sort synthesis and crystal structure of 1,3-bis­{[n,n-bis­(2-hy­droxy­eth­yl)amino]­meth­yl}-5-{[(4,6-di­methyl­pyridin-2-yl)amino]­meth­yl}-2,4,6-tri­ethyl­benzene
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361370/
https://www.ncbi.nlm.nih.gov/pubmed/35974834
http://dx.doi.org/10.1107/S2056989022007411
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