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Crystal structure and Hirshfeld surface analysis of (±)-N′-(2-hy­droxy-3-meth­oxy­benzyl­idene)-2-(4-iso­butyl­phen­yl)propionohydrazide

The title mol­ecule, C(21)H(26)N(2)O(3), adopts a V-shaped conformation and is chiral at the C atom with methyl group attached at the common cut of the edges of the V-conformation and crystallizes as a racemate. It also contains an intra­molecular O—H⋯N hydrogen bond. In the crystal, N—H⋯O hydrogen...

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Detalles Bibliográficos
Autores principales: Mohamed, Shaaban K., Mague, Joel T., Akkurt, Mehmet, Abdel-Rahman, Laila H., Abdel-Hameed, Mohamed, Albayati, Mustafa R., Al-Taif, Elham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361381/
https://www.ncbi.nlm.nih.gov/pubmed/35974829
http://dx.doi.org/10.1107/S2056989022007605
Descripción
Sumario:The title mol­ecule, C(21)H(26)N(2)O(3), adopts a V-shaped conformation and is chiral at the C atom with methyl group attached at the common cut of the edges of the V-conformation and crystallizes as a racemate. It also contains an intra­molecular O—H⋯N hydrogen bond. In the crystal, N—H⋯O hydrogen bonds form chains of mol­ecules extending along the c-axis direction, together with normal van der Waals contacts. The roles of the various inter­molecular inter­actions were clarified by Hirshfeld surface analysis, which reveals that the most important contributions to the crystal packing are from H⋯H (62.6%), C⋯H/H⋯C (15.8%) and O⋯H/H⋯O (15.3%) contacts.