Cargando…

Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium

BACKGROUND: Calmodulin (CaM) is an evolutionarily conserved eukaryotic multifunctional protein that functions as the major sensor of intracellular calcium signaling. Its calcium-modulated function regulates the activity of numerous effector proteins involved in a variety of physiological processes i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Léger, Corentin, Pitard, Irène, Sadi, Mirko, Carvalho, Nicolas, Brier, Sébastien, Mechaly, Ariel, Raoux-Barbot, Dorothée, Davi, Maryline, Hoos, Sylviane, Weber, Patrick, Vachette, Patrice, Durand, Dominique, Haouz, Ahmed, Guijarro, J. Iñaki, Ladant, Daniel, Chenal, Alexandre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361521/ https://www.ncbi.nlm.nih.gov/pubmed/35945584 http://dx.doi.org/10.1186/s12915-022-01381-5

Ejemplares similares

A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells
por: Voegele, Alexis, et al.
Publicado: (2021)

Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis
por: O’Brien, Darragh P., et al.
Publicado: (2017)

B2LiVe, a label-free 1D-NMR method to quantify the binding of amphitropic peptides or proteins to membrane vesicles
por: Sadi, Mirko, et al.
Publicado: (2023)

The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro
por: Voegele, Alexis, et al.
Publicado: (2019)

A Robust and Sensitive Spectrophotometric Assay for the Enzymatic Activity of Bacterial Adenylate Cyclase Toxins
por: Davi, Marilyne, et al.
Publicado: (2022)

Down Regulation of Catsper1 Expression by Calmodulin Inhibitor (Calmidazolium): Possible Implications for Fertility
por: Forero-Forero, Angela, et al.
Publicado: (2022)

Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion
por: O’Brien, Darragh P., et al.
Publicado: (2015)

Stability, structural and functional properties of a monomeric, calcium–loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis
por: Cannella, Sara E., et al.
Publicado: (2017)

A Tethered Bilayer Assembled on Top of Immobilized Calmodulin to Mimic Cellular Compartmentalization
por: Rossi, Claire, et al.
Publicado: (2011)

Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin
por: Raoux-Barbot, Dorothée, et al.
Publicado: (2018)

Prevalence of ExoY Activity in Pseudomonas aeruginosa Reference Panel Strains and Impact on Cytotoxicity in Epithelial Cells
por: Silistre, Hazel, et al.
Publicado: (2021)

Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin
por: Teixeira Nunes, Magda, et al.
Publicado: (2023)

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy
por: Chenal, Alexandre, et al.
Publicado: (2018)

Structural basis for haem piracy from host haemopexin by Haemophilus influenzae
por: Zambolin, Silvia, et al.
Publicado: (2016)

Antifungal Susceptibility Profiles of 1698 Yeast Reference Strains Revealing Potential Emerging Human Pathogens
por: Desnos-Ollivier, Marie, et al.
Publicado: (2012)

Cryptococcosis Serotypes Impact Outcome and Provide Evidence of Cryptococcus neoformans Speciation
por: Desnos-Ollivier, Marie, et al.
Publicado: (2015)

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
por: Belyy, Alexander, et al.
Publicado: (2016)

Analyzing In Silico the Relationship Between the Activation of the Edema Factor and Its Interaction With Calmodulin
por: Pitard, Irène, et al.
Publicado: (2020)

Disorder-to-Order Transition in the CyaA Toxin RTX Domain: Implications for Toxin Secretion
por: Sotomayor-Pérez, Ana-Cristina, et al.
Publicado: (2014)

Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region
por: Voegele, Alexis, et al.
Publicado: (2017)

Mapping the Site of Action of Human P2X7 Receptor Antagonists AZ11645373, Brilliant Blue G, KN-62, Calmidazolium, and ZINC58368839 to the Intersubunit Allosteric Pocket
por: Bin Dayel, Anfal, et al.
Publicado: (2019)

Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin
por: Angely, Christelle, et al.
Publicado: (2020)

High-Throughput Crystallization Pipeline at the Crystallography Core Facility of the Institut Pasteur
por: Weber, Patrick, et al.
Publicado: (2019)

Calmodulin and Calmodulin Binding Proteins in Dictyostelium: A Primer
por: O’Day, Danton H., et al.
Publicado: (2020)

Calmodulin-dependent and calmodulin-independent glutamate decarboxylases in apple fruit
por: Trobacher, Christopher P, et al.
Publicado: (2013)

The role of calmodulin and calmodulin-dependent protein kinases in the pathogenesis of atherosclerosis
por: Chen, Mei-Fang
Publicado: (2021)

Purification of calmodulin from Chlamydomonas: calmodulin occurs in cell bodies and flagella
Publicado: (1980)

Human Calmodulin Methyltransferase: Expression, Activity on Calmodulin, and Hsp90 Dependence
por: Magen, Sophia, et al.
Publicado: (2012)

Involvement of calmodulin and calmodulin-like proteins in plant responses to abiotic stresses
por: Zeng, Houqing, et al.
Publicado: (2015)

Characterization and Functional Analysis of Calmodulin and Calmodulin-Like Genes in Fragaria vesca
por: Zhang, Kai, et al.
Publicado: (2016)

Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins
por: Hamdi, Karama, et al.
Publicado: (2017)

Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity
por: Genera, Mariano, et al.
Publicado: (2023)

Human Calmodulin Mutations
por: Jensen, Helene H., et al.
Publicado: (2018)

Genome-Wide Identification and Analyses of Calmodulins and Calmodulin-like Proteins in Lotus japonicas
por: Liao, Jinqiu, et al.
Publicado: (2017)

Identification, characterization and expression analysis of calmodulin and calmodulin-like proteins in Solanum pennellii
por: Shi, Jinyan, et al.
Publicado: (2020)

Calmodulin and calmodulin-like gene family in barley: Identification, characterization and expression analyses
por: Cai, Kangfeng, et al.
Publicado: (2022)

Quality assessment and optimization of purified protein samples: why and how?
por: Raynal, Bertrand, et al.
Publicado: (2014)

MEMHDX: an interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets
por: Hourdel, Véronique, et al.
Publicado: (2016)

Function of a calmodulin in postsynaptic densities. III. Calmodulin- binding proteins of the postsynaptic density
Publicado: (1981)

Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex
por: Alaimo, Alessandro, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_hh2bcb8q0m6c1ici437a7ipiln